L1012

Linoleic acid

liquid, BioReagent, suitable for cell culture

• 동의어(들): cis-9,cis-12-Octadecadienoic acid
• Linear Formula: CH₃(CH₂)₄CH=CHCH₂CH=CH(CH₂)₇CO₂H
• CAS Number: 60-33-3
• Molecular Weight: 280.45
• Beilstein: 1727101
• EC Number: 200-470-9
• MDL number: MFCD00064241
• UNSPSC 코드: 12352211
• eCl@ss: 32190102
• PubChem Substance ID: 24896270
• NACRES: NA.75

속성

• 생물학적 소스: plant (Safflower oil)
• Quality Level: 200
• 제품 라인: BioReagent
• 분석: ≥98%
• 양식: liquid
• 기술: cell culture | mammalian: suitable
• refractive index: n20/D 1.466 (lit.)
• bp: 229-230 °C/16 mmHg (lit.)
• mp: −5 °C (lit.)
• solubility: NaOH: 1 M; ethanol: soluble
• density: 0.902 g/mL at 25 °C (lit.)
• 저장 온도: −20°C
• SMILES string: OC(CCCCCCC/C=C\C/C=C\CCCCC)=O
• InChI: 1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-
• InChI key: OYHQOLUKZRVURQ-HZJYTTRNSA-N
• 유전자 정보: human ... SOAT1(6646) , SOAT2(8435)

설명

일반 설명

Linoleic acid (LA) is the precursor for the synthesis of arachidonic prostaglandins and other eicosanoids. LA is present in vegetable oils and meat.

애플리케이션

Fatty acid that is typically bound to a carrier molecule such as BSA or cyclodextrin for use in cell culture.

Linoleic acid has been used as a component of S12 medium for cardiomyocytes differentiation, minimum essential medium α for spermatogonial stem cell culture and for endothelial differentiation of mouse adipose-derived stem cells (mASC).

생화학적/생리학적 작용

Linoleic acid (LA) may improve wound healing in diabetic rat. The levels of LA in adipose tissue and platelets are correlated with coronary artery disease. It may induce tumor and apoptosis in colorectal cancer cells. Studies also support their protective effects in lymphocytes. Linoleic acid is typically bound to a carrier molecule such as bovine serum albumin (BSA) or cyclodextrin for use in cell culture.

Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes .

포장

Sealed ampule.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)