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Merck
모든 사진(1)

문서

T1157

Sigma-Aldrich

(+)-α-Tocopherol acetate

BioReagent, suitable for insect cell culture, ~1360 IU/g

동의어(들):

Vitamin E acetate

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C31H52O3
CAS Number:
58-95-7
Molecular Weight:
472.74
EC Number:
200-405-4
MDL number:
MFCD00072052
UNSPSC 코드:
12352205
eCl@ss:
34058007
PubChem Substance ID:
24899940
NACRES:
NA.75

생물학적 소스

plant

설명

Synthesized from natural α-tocopherol

제품 라인

BioReagent

형태

liquid (or semi-solid)

특이 활성도

~1360 IU/g

분자량

Mw 472.74 g/mol

정제법

crystallization

기술

cell culture | insect: suitable

색상

white to yellow

solubility

chloroform: soluble 50 mg/mL, clear, colorless to yellow

저장 온도

room temp

SMILES string

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1

InChI

1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1

InChI key

ZAKOWWREFLAJOT-CEFNRUSXSA-N

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관련 카테고리

일반 설명

α-Tocopherol acetate is a semisynthetic acetate ester of naturally occurring α-tocopherol.

애플리케이션

(+)-α-Tocopherol acetate has been used:
  • as a supplement in the human embryonic kidney cells (HEK 293) to assess its impact on cell growth
  • as a component of Dulbecco′s Modified Eagle Medium/Nutrient Mixture F-12 (DMEM/F12) for immortalized chondrocyte cell line
  • as a component of serum-free medium for human colon tissue organ culture
  • to test its antioxidant effects on cow articular chondrocytes

Use in insect cell culture applications as an antioxidant.

생화학적/생리학적 작용

α-Tocopherol acetate or vitamin E-acetate has antioxidant properties and reduces lipid peroxidation. However, vitamin E acetate on pyrolysis leads to the generation of carcinogens like alkenes and benzenes.

주의사항

Since the M.P. is about 25 °C this preparation is usually an oil. Does not air oxidize.

유해 및 위험 성명서

H413

예방조치 성명서

P273 - P501

Hazard Classifications

Aquatic Chronic 4

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

개인 보호 장비

Eyeshields, Gloves

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Optimization of HEK 293 cell growth by addition of non-animal derived components using design of experiments.
Laura Cervera et al.
BMC proceedings, 5 Suppl 8, P126-P126 (2012-03-01)
Role of vitamin E-acetate on cisplatin induced genotoxicity: An in vivo analysis
Mazumdar M, et al.,
Central European Journal of Biology, 7(2), 334-342 (2012)
Michael K Dame et al.
In vitro cellular & developmental biology. Animal, 47(1), 32-38 (2010-11-26)
We have recently shown that a multi-mineral extract from the marine red algae, Lithothamnion calcareum, suppresses colon polyp formation and inflammation in mice. In the present study, we used intact human colon tissue in organ culture to compare responses initiated
Horst Claassen et al.
Cell and tissue research, 319(3), 439-445 (2005-01-26)
Osteoarthritis (OA) is aggravated in menopausal women possibly because of changed serum estrogen levels. Estradiol has been postulated to affect oxidative stress induced by reactive oxygen species (ROS) in articular chondrocytes. We generated ROS in cultured bovine articular chondrocytes by
Michael K Dame et al.
In vitro cellular & developmental biology. Animal, 46(2), 114-122 (2009-11-17)
Normal and neoplastic human colon tissue obtained at surgery was used to establish conditions for organ culture. Optimal conditions included an atmosphere of 5% CO2 and 95% O2; tissue partially submerged with mucosa at the gas interface; and serum-free medium
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