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Merck
모든 사진(2)

주요 문서

L2398

Sigma-Aldrich

Lactobionic acid

≥97% (TLC), cell impermeant agent

동의어(들):

4-O-β-D-Galactopyranosyl-D-gluconic acid

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About This Item

실험식(Hill 표기법):
C12H22O12
CAS Number:
Molecular Weight:
358.30
Beilstein:
95054
EC Number:
MDL number:
UNSPSC 코드:
12352201
PubChem Substance ID:
NACRES:
NA.25

생물학적 소스

synthetic (organic

Organic)

Quality Level

분석

≥97% (TLC)

양식

powder

색상

white

mp

113-118 °C (lit.)

solubility

water: 50 mg/mL, clear, colorless

저장 온도

room temp

SMILES string

OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C(O)=O

InChI

1S/C12H22O12/c13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h3-10,12-20H,1-2H2,(H,21,22)/t3-,4-,5+,6+,7-,8-,9-,10-,12+/m1/s1

InChI key

JYTUSYBCFIZPBE-AMTLMPIISA-N

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일반 설명

Lactobionic acid, a derivative of lactose, is an aldonic acid obtained from gluconic acid and galactose. It is a potential chelating agent, preservative and a prebiotic.

애플리케이션

Cell impermeant agent used for organ preservation
Lactobionic acid has been used as a control for the chemical characterization of the lactobionic acid produced by Zymomonas mobilis.

생화학적/생리학적 작용

Lactobionic acid has a role as an antioxidant and stabilizer-gelling agent. It is used as an ingredient in foods and pharmaceutical products.
Reported to inhibit production of hydroxyl radicals. Cryptic inhibitor of matrix metalloproteinases (MMP). Resistant to dietary metabolism but stimulates intestinal calcium absorption in rat.

기타 정보

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

J H Southard et al.
Annual review of medicine, 46, 235-247 (1995-01-01)
Organ preservation is the supply line for organ transplantation. Currently, the liver, pancreas, and kidney can be successfully preserved for up to two days by flushing the organs with the University of Wisconsin (UW) organ preservation solution and storing them
Lactobionic acid produced by Zymomonas mobilis: alternative to prepare targeted nanoparticles
Valle TA, et al.
Pharmaceutica Analytica Acta, 4, 1-5 (2013)
J A Wahlberg et al.
Transplantation, 43(1), 5-8 (1987-01-01)
A new flushout solution for preservation of the pancreas was tested in the dog model of segmental pancreas autotransplantation. The solution osmolality was 320 mOsm/L, K+ = 120 mM, Na+ = 30 mM, and it contained the anion, lactobionate, and
R Brommage et al.
The Journal of nutrition, 123(12), 2186-2194 (1993-12-01)
Lactulose is a disaccharide analogue of lactose that is resistant to metabolism in the small intestine but not in the large intestine. The effects of lactulose and other sugars on intestinal Ca absorption were determined from the decrease in the
C Charloux et al.
Free radical biology & medicine, 19(5), 699-704 (1995-11-01)
Superoxide and hydroxyl free radicals are strongly implicated in the deleterious effects of reperfusion of grafted organs. Iron ions are critical in the Fenton-like reaction that generates oxygen-free radicals from H2O2. Using the ADP/Fe2+/H2O2 .OH-generating system, we demonstrated that components

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