M3696

Anti-MAP2 Antibody

rabbit polyclonal

• 동의어(들): Anti-Microtubule associated protein 2
• MDL number: MFCD00164683
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 제품명: Anti-MAP2 antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution
• 생물학적 소스: rabbit
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: antigen ~280 kDa; antigen ~72 kDa
• 종 반응성: rat, mouse, human
• 농도: ~1 mg/mL
• 기술: flow cytometry: 1:200-1:500; immunohistochemistry: 1:100-1:200; western blot: 1:500-1:1,000
• UniProt 수납 번호: P11137
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... MAP2(4133) ; mouse ... Mtap2(17756) ; rat ... Map2(25595)

설명

일반 설명

MAP2 is a microtubule-associated protein that regulates the structure and function of the cytoskeleton. The protein also modulates morphogenesis of neurons and cell proliferation. Interactions of MAP2 with F-actin have been implicated in neurite initiation and microtubular re-organization. Decreased levels of MAP2 have been associated with transmissible spongiform encephalopathies . Anti-MAP2 antibody is specific for MAP2 in human, mice and rats.

Microtubule associated protein 2 (MAP2) is a neuron specific protein, which is highly expressed in the central nervous system. It is the member of cytoskeletal proteins. The gene is located on human chromosome 2q34.

면역원

synthetic peptide corresponding to residues 2-15 of human MAP2.

애플리케이션

Anti-MAP2 antibody is suitable for use in immunohistochemistry (1:500 using Zamboni′s fixative-fixed, frozen mouse spinal cord and thalamus sections) , flow cytometry (1:200-1:500), immunoblotting (approx. 72 kDa and 280 kDa) and western blot (1:500-1:1,000).

Anti-MAP2 antibody produced in rabbit has been used in immunocytochemistry.

생화학적/생리학적 작용

Microtubule associated protein 2 (MAP2) plays a critical role in the formation of dendritic protrusions in astrocytes and oligodendrocytes. It maintains the homeostasis of microtubules. The protein plays an important role in neuronal plasticity.

물리적 형태

solution in phosphate buffered saline, containing 0.02% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)