추천 제품
사용
sufficient for 100 colorimetric or fluorometric tests
검출 방법
colorimetric
fluorometric
관련 질환(들)
cancer; cardiovascular diseases; hematological disorder
저장 온도
−20°C
일반 설명
Sialic Acid is a general name for nine carbon acidic sugars with N- or O-substituted derivatives. The most common member of these sugars is N-acetylneuraminic acid (NANA). They are associated with carbohydrates and are localized on cell membranes. Sialic acid is widely distributed throughout mammalian tissues and fluids including serum. Sialylated oligosaccharides have been shown to exhibit antiviral properties and are also known to influence blood coagulation and cholesterol levels. The sialic acid level in body fluids is also an important marker for diagnosing cancer.
애플리케이션
- Evaluation of serum total sialic acid in moderate COVID-19 patients with and without gastrointestinal tract manifestations.: The study measures serum sialic acid levels in COVID-19 patients to understand the disease′s impact on the gastrointestinal tract (Haroun et al., 2022).
적합성
Suitable for the quantitative determination of free and total sialic acid (NANA) and evaluation of drug effects on sialic acid in serum, plasma, saliva, milk etc.
원리
This sialic acid assay uses an improved Warren method, in which sialic acid is oxidized to formylpyruvic acid. This reacts with thiobarbituric acid to form a pink colored product. The colorimetric (549nm)/fluorimetric (λex = 555nm/λem = 585nm) product is directly proportional to sialic acid concentration in the sample.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Aquatic Chronic 2 - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
Salivary total sialic acid levels increase in breast cancer patients: a preliminary study.
Ozturk L K, et al.
Medicinal Chemistry, 7(5), 443-447 (2011)
Sialic Acids
Varki A, et al.
Essentials Of Glycobiology. 2nd Edition. (2009)
Sialic acids: fascinating sugars in higher animals and man.
Schauer R.
Zoology (Jena, Germany), 107(1), 49-64 (2004)
Alice J Stelfox et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(43), 21514-21520 (2019-10-09)
The bat-borne paramyxovirus, Sosuga virus (SosV), is one of many paramyxoviruses recently identified and classified within the newly established genus Pararubulavirus, family Paramyxoviridae The envelope surface of SosV presents a receptor-binding protein (RBP), SosV-RBP, which facilitates host-cell attachment and entry.
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