P0393

Protein Kinase Inhibitor from porcine heart

1-3 inhibitor U/μg protein, lyophilized powder

• MDL number: MFCD00132115
• UNSPSC 코드: 12352202

속성

• 생물학적 소스: Porcine heart
• 양식: lyophilized powder
• 특이 활성도: 1-3 inhibitor U/μg protein
• 구성: Protein, ~50% biuret
• 저장 온도: 2-8°C

설명

생화학적/생리학적 작용

These proteins bind to the catalytic subunit of cyclic-AMP dependent protein kinase, displacing the regulatory subunit and inhibiting phosphorylating activity. The cyclic-AMP binding capacity of the regulatory subunit is enhanced. Many other proteins exhibit this enhancement ability, too (Brostrom, C.O. and Kon, C., Anal. Biochem., 58, 459 [1974]).

포장

Package size based on protein content.

단위 정의

One unit will transfer 1.0 picomole (10^-12 mol) of phosphate from γ-³²P-ATP to hydrolyzed and partially dephosphorylated casein (Product No. C 4765) per min at pH 6.5 at 30 °C.

물리적 형태

Supplied as lyophilized powder containing 30% glycerophosphate and 20% EDTA.

제조 메모

Fractionated essentially by procedure of Walsh, D.A., et al., J. Biol. Chem., 246, 1977 (1971).

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)