P6004

Prednisolone

≥99% (HPLC), powder, glucocorticoid

• 동의어(들): 1,4-Pregnadiene-11β,17α,21-triol-3,20-dione, 1-Dehydrocortisol, 1-Dehydrohydrocortisone, 11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione
• 실험식(Hill 표기법): C₂₁H₂₈O₅
• CAS Number: 50-24-8
• Molecular Weight: 360.44
• Beilstein: 1354103
• EC Number: 200-021-7
• MDL number: MFCD00003649
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24898725
• NACRES: NA.77

속성

• product name: Prednisolone, ≥99%
• 생물학적 소스: synthetic (organic)
• Quality Level: 200
• 무균: non-sterile
• 분석: ≥99%
• 형태: powder
• mp: 240 °C (dec.) (lit.)
• solubility: chloroform: methanol (1:1): 50 mg/mL, clear, colorless to faintly yellow
• 주관자: Johnson & Johnson
• 배송 상태: ambient
• 저장 온도: room temp
• SMILES string: O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(CO)=O)=C1
• InChI: 1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
• InChI key: OIGNJSKKLXVSLS-VWUMJDOOSA-N
• 유전자 정보: human ... AR(367) , ESR1(2099) , NR3C1(2908) , NR3C2(4306) , PGR(5241) , SERPINA6(866) ; mouse ... Nr3c1(14815) ; rat ... Ar(24208)

설명

일반 설명

Prednisolone prevents protease activity in vitro. It stimulates myogenesis and inhibits apoptosis. Prednisolone is used to treat Duchenne muscular dystrophy (DMD), gout arthritis and chronic obstructive pulmonary disease (COPD) exacerbations.

애플리케이션

Prednisolone has been used for the Δ¹-dehydrogenation of hydrocortisone by gel entrapped arthrobacter simplex cells.

생화학적/생리학적 작용

Prednisolone is a glucocorticoid with anti-inflammatory and immunosuppressive activity.

특징 및 장점

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

분석 메모

Actual content given on label

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H360FD
• 예방조치 성명서: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves