P6254

Prednisone

≥98% (HPLC), powder, anti-inflammatory activity

• 동의어(들): 1,4-Pregnadiene-17α,21-diol-3,11,20-trione, 1-Cortisone, 17α,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione, Dehydrocortisone
• 실험식(Hill 표기법): C₂₁H₂₆O₅
• CAS Number: 53-03-2
• Molecular Weight: 358.43
• Beilstein: 2065301
• EC Number: 200-160-3
• MDL number: MFCD00003608
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24898748
• NACRES: NA.77

속성

• 제품명: Prednisone, ≥98%
• 생물학적 소스: synthetic
• Quality Level: 200
• 무균: non-sterile
• 분석: ≥98%
• 양식: powder
• mp: 236-238 °C (lit.)
• solubility: chloroform/ethanol (1:1): 50 mg/mL, clear, colorless to light yellow
• 응용 분야: hematology
• 배송 상태: ambient
• 저장 온도: room temp
• SMILES string: O=C1C=C[C@@]2(C)C(CC[C@]([C@@](CC[C@@]3(C(CO)=O)O)([H])[C@]3(C)C4)([H])[C@]2([H])C4=O)=C1
• InChI: 1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
• InChI key: XOFYZVNMUHMLCC-ZPOLXVRWSA-N
• 유전자 정보: human ... NR3C1(2908)

설명

애플리케이션

Prednisone has been used in dimethyl sulfoxide stock suspension to inject into experimental mice and to analyze the effects of glucocorticoid steroid. It has also been used as a test drug, formulated with peanut butter to study the effects of daily administration of MIDD0301, by animal weight, organ weight and haematological analysis.

생화학적/생리학적 작용

Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activity. It is useful in treating many disease states and has a half-life of 3.4 to 3.8 hours in plasma. Prednisone is metabolized to prednisolone, which is physiologically active.

특징 및 장점

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS08
• 신호어: Warning
• 유해 및 위험 성명서: H373
• 예방조치 성명서: P260 - P314 - P501
• Hazard Classifications: STOT RE 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• 개인 보호 장비: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges