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Merck
모든 사진(1)

주요 문서

P7252

Sigma-Aldrich

Phospho(enol)pyruvic acid tri(cyclohexylammonium) salt

≥98% (enzymatic), powder

동의어(들):

2-(Phosphonooxy)-2-propenoic acid tri(cyclohexylammonium) salt, PEP-3CHA, Phosphoenolpyruvic acid tris(cyclohexylamine) salt

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About This Item

실험식(Hill 표기법):
C3H5O6P · 3C6H13N
CAS Number:
Molecular Weight:
465.56
Beilstein:
3752336
EC Number:
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.83

product name

Phospho(enol)pyruvic acid tri(cyclohexylammonium) salt, ≥98% (enzymatic)

Quality Level

분석

≥98% (enzymatic)

형태

powder

solubility

water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

저장 온도

−20°C

SMILES string

NC1CCCCC1.NC2CCCCC2.NC3CCCCC3.OC(=O)C(=C)OP(O)(O)=O

InChI

1S/3C6H13N.C3H5O6P/c3*7-6-4-2-1-3-5-6;1-2(3(4)5)9-10(6,7)8/h3*6H,1-5,7H2;1H2,(H,4,5)(H2,6,7,8)

InChI key

MJKYGUXBFYGLLM-UHFFFAOYSA-N

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일반 설명

Phospho(enol)pyruvic acid is a highly functionalized small molecule. It plays a major role in the metabolism.

애플리케이션

Phospho(enol)pyruvic acid tri(cyclohexylammonium) salt has been used:
  • in the pyruvate kinase/lactate dehydrogenase enzyme kinetic assay
  • in the reaction mixture to determine fructokinase activity of Zobellia galactanivorans
  • in luminometry to determine the amount of ADP formed by measuring the increase in light output

생화학적/생리학적 작용

Phospho(enol)pyruvic acid is significant in high-phosphate group-transfer function. PEP plays a major role in PEP:sugar phosphotransferase system (PTS) mediated phosphorylation and transport of carbohydrates across the bacterial membrane. It functions to generate natural phosphonates catalyzed by PEP mutase. It plays a key role in the peptidoglycan cell wall biosynthesis.
Phospho(enol)pyruvic acid (PEP) is involved in glycolysis and gluconeogenesis. In glycolysis, PEP is metabolized by pyruvate kinase to yield pyruvate. In plants, PEP is involved in the formation of aromatic amino acids as well as in the carbon fixation pathway.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

Determination of Fructokinase Activity from Zobellia galactanivorans
Groisillier A and Tonon T
Bio-protocol, 5(21), e1633-e1633 (2015)
Secretion from dense granules
Methods in Molecular biology: Platelets and Megakaryocytes, volume 1, functional assays, 89-91 (2004)
Structural basis for kinase-mediated macrolide antibiotic resistance
Fong DH, et al.
Structure, 25(5), 750-761 (2017)
Synthesis of phosphoenol pyruvate (PEP) analogues and evaluation as inhibitors of PEP-utilizing enzymes
Garcia-Alles LF and Erni B
European Journal of Biochemistry, 269(13), 3226-3236 (2002)
Jan Niemann et al.
Free radical biology & medicine, 102, 174-187 (2016-11-29)
Mitochondrial dysfunction affects liver metabolism, but it remains unclear whether this interferes with normal liver aging. We investigated several mitochondrial pathways in hepatocytes and liver tissue from a conplastic mouse strain compared with the control C57BL/6NTac strain over 18 months

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