추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
IgG fraction of antiserum
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
77039 Da
종 반응성
human
기술
immunofluorescence: 1:10-1:50
immunohistochemistry: 1:50-1:100
western blot: 1:1000
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... UBC(7316)
일반 설명
Ubiquitin, also known as ubiquitin C (UBC), is a globular protein, encoded by the gene mapped to human chromosome 12q24.31. The encoded protein consists of 76 amino acids.
면역원
a synthetic peptide between 36-66 amino acids of human Ubiquitin, which is in the Ubiquitin-like 1 domain
애플리케이션
Anti-ubiquitin antibody produced in rabbit has been used in western blotting.
생화학적/생리학적 작용
Ubiquitin plays a major role in protein degradation. Ubiquitin-mediated degradation of regulatory proteins has been implicated in the regulation of various processes, such as cell-cycle progression, signal transduction, transcriptional regulation, receptor down-regulation and endocytosis. Aberrations in the ubiquitin-mediated pathways contribute to malignant transformation.
물리적 형태
Supplied in PBS with 0.09% (W/V) sodium azide
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
이미 열람한 고객
Localization of the human UBC polyubiquitin gene to chromosome band 12q24.3.
Board PG, et al.
Genomics, 12, 639-642 (1992)
Ubiquitin recognition by the proteasome
Saeki Y, et al.
Journal of Biochemistry, 161, 113-124 (2017)
The VHL short variant involves in protein quality control
Liu Y, et al.
Gene, 589, 63-71 (2016)
Jia-Hua Qu et al.
eLife, 12 (2024-01-22)
Our prior study (Tarasov et al., 2022) discovered that numerous adaptive mechanisms emerge in response to cardiac-specific overexpression of adenylyl cyclase type 8 (TGAC8) which included overexpression of a large number of proteins. Here, we conducted an unbiased phosphoproteomics analysis
A Hershko et al.
Annual review of biochemistry, 67, 425-479 (1998-10-06)
The selective degradation of many short-lived proteins in eukaryotic cells is carried out by the ubiquitin system. In this pathway, proteins are targeted for degradation by covalent ligation to ubiquitin, a highly conserved small protein. Ubiquitin-mediated degradation of regulatory proteins
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