SAB4200197
Anti-Periostin antibody,Mouse monoclonal
clone 47, purified from hybridoma cell culture
동의어(들):
Periostin Antibody, Periostin Antibody - Monoclonal Anti-Periostin antibody produced in mouse, Anti-OSF2, Anti-Osteoblast specific factor 2, Anti-PDLPOSTN, Anti-POSTN
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모든 사진(1)
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.41
추천 제품
생물학적 소스
mouse
결합
unconjugated
항체 형태
purified from hybridoma cell culture
항체 생산 유형
primary antibodies
클론
47, monoclonal
양식
buffered aqueous solution
분자량
antigen ~88 kDa
종 반응성
human
농도
~1.0 mg/mL
기술
western blot: 2-4 μg/mL using whole extracts of HEK-293T cells over expressing human Periostin
동형
IgG1
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... POSTN(10631)
일반 설명
Periostin (POSTN) is also known as osteoblast-specific factor-2. It is a 90 kDa protein expressed in the extracellular matrix and bones. POSTN is an adhesive glycoprotein. The gene encoding this protein is localized on human chromosome 13q13.3.
면역원
human Periostin recombinant protein. The human protein shares 87% homology with the mouse protein.
애플리케이션
Monoclonal Anti-Periostin antibody produced in mouse has been used to develop a periostin imaging PET probe.
생화학적/생리학적 작용
Periostin (POSTN) has a role in the differentiation and cell adhesion of osteogenic cells. It functions as a biomarker of T-helper cells type 2-mediated inflammatory diseases. The protein has been associated with various cancers. POSTN is involved in epithelial-mesenchymal transition and extracellular matrix degradation.
물리적 형태
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Functional role of periostin in development and wound repair: implications for connective tissue disease.
Hamilton D W.
Journal of Cell Communication and Signaling, 2(1-2), 9-9 (2008)
Imaging of secreted extracellular periostin, an important marker of invasion in the tumor microenvironment in esophageal cancer.
Heidari P, et al.
Journal of Nuclear Medicine, 56(8), 1246-1246 (2015)
Mechanism of Periostin Production in Human Bronchial Smooth Muscle Cells.
Makita K, et al.
International Archives of Allergy and Immunology, 175(1-2), 26-35 (2018)
Deepraj Ghosh et al.
Journal of cell science, 133(2) (2020-01-15)
Mesenchymal stem cells (MSCs) are essential for the regenerative process; however, biological aging and environmental stress can induce senescence - an irreversible state of growth arrest - that not only affects the behavior of cells but also disrupts their ability
Epithelial periostin expression is correlated with poor survival in patients with invasive breast carcinoma.
Kim G E, et al.
PLoS ONE, 12(11), e0187635-e0187635 (2017)
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