SAB4200721

Anti-GABA antibody, Mouse monoclonal

clone GB-69, purified from hybridoma cell culture

• 동의어(들): Mouse Anti-Gamma-aminobutyric acid
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 200
• 항체 형태: purified from hybridoma cell culture
• 항체 생산 유형: primary antibodies
• 클론: GB-69, monoclonal
• 양식: buffered aqueous solution
• 종 반응성: rat, monkey, frog, mouse, human, gerbil
• 농도: ~1.0 mg/mL
• 기술: ELISA: suitable; dot blot: suitable; immunofluorescence: 5-10 μg/mL using human pancreatic tumor AsPC1 cell line; immunohistochemistry: 1-2.5 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded human brain and/or cerebellum sections
• 동형: IgG1
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... GABRA1(2554) ; mouse ... Gabra1(14394) ; rat ... Gabra1(29705) ; rhesus monkey ... Gabra1(574302)

설명

일반 설명

Anti-GABA antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the GB-69 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a mouse immunized with purified GABA conjugated to BSA. γ-Aminobutyric acid (GABA) is present in the central nervous system (CNS) of vertebrates. GABA is formed following enzymatic decarboxylation of L-glutamic acid by glutamic acid decarboxylase (GAD).

면역원

purified GABA conjugated to BSA

애플리케이션

Anti-GABA antibody, Mouse monoclonal has been used in:

• immunofluorescence
• immunohistochemistry
• enzyme linked immunosorbent assay (ELISA)
• dot-blot

생화학적/생리학적 작용

γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter. GABA mediates fast synaptic inhibition in the mature nervous system and plays multiple key roles as sensory circuits undergo functional development. GABA promotes proliferation of immune cells, embryonic stem cells and cortical progenitor cells. In addition, it is involved in protein synthesis and metabolism and plays a major role in the regulation of muscle tone, blood pressure, heart rate and respiration.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable