SRE0069

Phosphoglucomutase from rabbit muscle

• 동의어(들): α-D-Glucose-1,6-bisphosphatase, α-D-Glucose-1-phosphate phosphotransferase
• CAS Number: 9001-81-4
• 효소 위원회 번호: 5.4.2.2 (BRENDA, IUBMB)
• MDL number: MFCD00131886
• UNSPSC 코드: 12352204
• NACRES: NA.32

속성

• 형태: lyophilized powder
• Quality Level: 200
• 특이 활성도: ≥100 units/mg protein
• 외래 활성: Lactic dehydroenase ≤0.5%; Phosphoglucose Isomerase ≤0.01%; pyruvate kinase ≤0.05%
• 배송 상태: wet ice
• 저장 온도: −20°C

설명

일반 설명

Research area: CellSignalling. The phosphoglucomutase (PGM) molecule, a single polypeptide chain, is made up of four α/β domains. The domains form a compact heart-shaped structure with a large fissure between the two lobes, and the molecule comprises about 40 secondary structural components. The active enzymatic site of the molecule is located at the bottom of the crevice on the surface of domain I. Rabbit muscle phosphoglucomutase (RB-PGM) is a monomer with a unique four-domain architecture.

애플리케이션

Phosphoglucomutase from rabbit muscle may be used in dephosphorylation to investigate the hexose bisphosphate activation of phosphoglucomutase.

생화학적/생리학적 작용

Phosphoglucomutase (PGM) mainly catalyzes the interconversion of glucose 1-phosphate and glucose 6-phosphate via a glucose 1,6-diphosphate intermediate. Hence it plays a key role in glycolysis and gluconeogenesis.

단위 정의

One unit will convert 1.0 μmole of α-D-glucose 1-phosphate to α-D-glucose 6-phosphate per min at pH 7.4 at 30 °C.

물리적 형태

Lyophilized powder containing Tris HCl, EDTA, magnesium acetate and carbohydrate

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable