콘텐츠로 건너뛰기
Merck
모든 사진(1)

문서

T0397

Sigma-Aldrich

L-Thyroxine sodium salt pentahydrate

γ-irradiated, powder, BioXtra, suitable for cell culture

동의어(들):

3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt, Sodium levothyroxine, T4

로그인조직 및 계약 가격 보기
모든 사진(1)

About This Item

Linear Formula:
HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O
CAS Number:
6106-07-6
Molecular Weight:
888.93
Beilstein:
5721845
EC Number:
200-221-4
MDL number:
MFCD00149110
UNSPSC 코드:
12352209
PubChem Substance ID:
24899887
NACRES:
NA.77

생물학적 소스

synthetic (organic)

Quality Level

200

무균

γ-irradiated

제품 라인

BioXtra

분석

≥98%

형태

powder

효능

5-50 ng/mL

기술

cell culture | mammalian: suitable

mp

207-210 (dec.) (lit.)

solubility

cell culture medium: 0.1 mg/mL
H2O: soluble

저장 온도

−20°C

SMILES string

O.O.O.O.O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O

InChI

1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-1/t12-;;;;;;/m0....../s1

InChI key

JMHCCAYJTTWMCX-QWPJCUCISA-M

유전자 정보

mouse ... Cnr2(12802)
rat ... Cnr1(25248)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

생화학적/생리학적 작용

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.

물리적 형태

powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw, solution stable 2-8 °C, 30 days

재구성

To prepare 20 μg/ml stock solution, add 50 ml sterile culture medium.

픽토그램

Health hazard
GHS08

신호어

Danger

유해 및 위험 성명서

H372

예방조치 성명서

P260 - P264 - P270 - P314 - P501

Hazard Classifications

STOT RE 1

표적 기관

Thyroid,Cardio-vascular system,Kidney

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Giuseppe Ianiri et al.
mBio, 6(2) (2015-04-02)
Fungal diseases represent a major burden to health care globally. As with other pathogenic microbes, there is a limited number of agents suitable for use in treating fungal diseases, and resistance to these agents can develop rapidly. Cryptococcus neoformans is
Lilian Pukk et al.
Molecular ecology resources, 15(5), 1145-1152 (2015-02-24)
Massively parallel sequencing a small proportion of the whole genome at high coverage enables answering a wide range of questions from molecular evolution and evolutionary biology to animal and plant breeding and forensics. In this study, we describe the development
Mahdokht Jouiaei et al.
Molecular biology and evolution, 32(6), 1598-1610 (2015-03-12)
Despite Cnidaria (sea anemones, corals, jellyfish, and hydroids) being the oldest venomous animal lineage, structure-function relationships, phyletic distributions, and the molecular evolutionary regimes of toxins encoded by these intriguing animals are poorly understood. Hence, we have comprehensively elucidated the phylogenetic
Laam Li et al.
BMC genomics, 16, 637-637 (2015-08-27)
Legionella pneumophila (Lp) is a water-borne opportunistic pathogen. In water, Lp can survive for an extended period of time until it encounters a permissive host. Therefore, identifying genes that are required for survival in water may help develop strategies to
Pelin Sahlén et al.
Genome biology, 16, 156-156 (2015-08-28)
Although the locations of promoters and enhancers have been identified in several cell types, we still have limited information on their connectivity. We developed HiCap, which combines a 4-cutter restriction enzyme Hi-C with sequence capture of promoter regions. Applying the
모든 관련된 서류 보기

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.