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Merck
모든 사진(1)

주요 문서

T2379

Sigma-Aldrich

Tubocurarine hydrochloride pentahydrate

≥97%

동의어(들):

(+)-Tubocurarine hydrochloride

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About This Item

실험식(Hill 표기법):
C37H41ClN2O6 · HCl · 5H2O
CAS Number:
Molecular Weight:
771.72
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

분석

≥97%

solubility

H2O: soluble 50 mg/ml, with heating as required, clear to slightly hazy, colorless to yellow
ethanol: soluble
methanol: soluble

저장 온도

2-8°C

SMILES string

O.O.O.O.O.Cl.[Cl-].COc1cc2CCN(C)[C@H]3Cc4ccc(Oc5c(O)c(OC)cc6CC[N+](C)(C)[C@H](Cc7ccc(O)c(Oc1cc23)c7)c56)cc4

InChI

1S/C37H40N2O6.2ClH.5H2O/c1-38-14-12-24-19-32(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-37-35-25(20-34(43-5)36(37)41)13-15-39(2,3)29(35)17-23-8-11-30(40)31(18-23)45-33;;;;;;;/h6-11,18-21,28-29H,12-17H2,1-5H3,(H-,40,41);2*1H;5*1H2/t28-,29+;;;;;;;/m0......./s1

InChI key

WMIZITXEJNQAQK-GGDSLZADSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Tubocurarine hydrochloride pentahydrate has been used as a acetylcholinesterase inhibitor (Ach) inhibitor in myotubes, muscle and as neuromuscular junction blocker in zebra fish embryos.

생화학적/생리학적 작용

Tubocurarine is a muscle relaxant and a nicotinic acetylcholine receptor antagonist. It can induce neuromuscular blocking.

특징 및 장점

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

제조 메모

Tubocurarine hydrochloride pentahydrate is soluble in water at 50 mg/ml (with heat as required) and yields a clear to slightly hazy, colorless to yellow solution. It is also soluble in methanol and ethanol.

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

The kinetics of inhibition of nicotinic acetylcholine receptors by (+)-tubocurarine and pancuronium
Wenningmann I and Dilger JP
Molecular Pharmacology, 60(4), 790-796 (2001)
Proteasome inhibition with bortezomib depletes plasma cells and autoantibodies in experimental autoimmune myasthenia gravis
Gomez A, et al.
Journal of immunology (Baltimore, Md. : 1950), 186(4), 2503-2513 (2011)
Resistance to d-Tubocurarine of the Rat Diaphragm as Compared to a Limb MuscleInfluence of Quantal Transmitter Release and Nicotinic Acetylcholine Receptors
Nguyen-Huu, T, et al.
Anesthesiology, 110(5), 1011-1015 (2009)
Proteasome inhibition with bortezomib depletes plasma cells and autoantibodies in experimental autoimmune myasthenia gravis
Muto A, et al.
Proceedings of the National Academy of Sciences of the USA, 108(13), 5425-5425 (2011)
Gerta Vrbova et al.
The European journal of neuroscience, 30(3), 366-375 (2009-08-07)
There are receptors on denervated Schwann cells that may respond to the neurotransmitters that are released from growth cones of regenerating motor axons. In order to ascertain whether the interaction of the transmitters and their receptors plays a role during

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