T6764

Triprolidine hydrochloride

≥99%

• 동의어(들): (E)-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride, trans-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride
• 실험식(Hill 표기법): C₁₉H₂₂N₂ · HCl
• CAS Number: 6138-79-0
• Molecular Weight: 314.85
• MDL number: MFCD00039044
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24277808
• NACRES: NA.77

속성

• Quality Level: 200
• 분석: ≥99%
• solubility: alcohol: soluble 1 in 1.5 of solvent; chloroform: soluble 1 in less than 1 of solvent; H₂O: soluble 50 mg/mL, clear, colorless to yellow
• 주관자: GlaxoSmithKline
• 저장 온도: 2-8°C
• SMILES string: CC(C=C1)=CC=C1/C(C2=NC=CC=C2)=C\CN3CCCC3.Cl
• InChI: 1S/C19H22N2.ClH/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21;/h2-3,6-12H,4-5,13-15H2,1H3;1H/b18-11+;
• InChI key: WYUYEJNGHIOFOC-NWBUNABESA-N
• 유전자 정보: human ... HRH1(3269)

설명

애플리케이션

Triprolidine has been used as a H1 histaminergic inhibitor to study its effect on long-term potentiation (LTP) in tuberomammillary nucleus (TMN) neurons.

생화학적/생리학적 작용

H₁ histamine receptor antagonist.

특징 및 장점

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

제조 메모

Triprolidine hydrochloride is soluble in water at 50 mg/ml and yields a clear, colorless to yellow solution. It is also soluble in alcohol (1 in 1.5 of solvent) and chloroform (1 in less than 1 of solvent).

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves