R101

Ranitidine hydrochloride

solid

• 실험식(Hill 표기법): C₁₃H₂₂N₄O₃S · HCl
• CAS Number: 66357-59-3
• Molecular Weight: 350.86
• EC Number: 266-333-0
• MDL number: MFCD00069339
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24277803
• NACRES: NA.77

속성

• 형태: solid
• 색상: tan
• solubility: H₂O: 1.8 mg/mL; 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 7.0 mg/mL
• 주관자: GlaxoSmithKline
• SMILES string: Cl[H].CN\C(NCCSCc1ccc(CN(C)C)o1)=C\[N+]([O-])=O
• InChI: 1S/C13H22N4O3S.ClH/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3;/h4-5,9,14-15H,6-8,10H2,1-3H3;1H/b13-9-;
• InChI key: GGWBHVILAJZWKJ-CHHCPSLASA-N
• 유전자 정보: human ... HRH2(3274)

설명

애플리케이션

Ranitidine hydrochloride has been used as a reference compound for the development and validation of parallel artificial membrane permeability assay (PAMPA).

생화학적/생리학적 작용

Ranitidine is mainly used to treat gastrointestinal impairment instigated by non-steroidal anti-inflammatory drugs (NSAIDs).

H₂ histamine receptor antagonist; anti-ulcer agent.

특징 및 장점

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H315,H317,H319,H334,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)