모든 사진(2)
About This Item
실험식(Hill 표기법):
C10H6N2O2
CAS Number:
Molecular Weight:
186.17
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
생물학적 소스
synthetic (organic)
Quality Level
분석
≥98%
형태
powder
효능
35 μM IC50
solubility
DMSO: soluble 50 mg/mL, clear, yellow to brownish-yellow
저장 온도
2-8°C
SMILES string
Oc1ccc(cc1O)\C=C(\C#N)C#N
InChI
1S/C10H6N2O2/c11-5-8(6-12)3-7-1-2-9(13)10(14)4-7/h1-4,13-14H
InChI key
VTJXFTPMFYAJJU-UHFFFAOYSA-N
유전자 정보
human ... CDK2(1017)
애플리케이션
Tyrphostin 23 can be used as a tyrosine kinase inhibitor for studying rat ghrelin-induced MAPK stimulation in GH3 cells. Tyrphostin 23 has also been used to analyze its effects on secretoneurin (SN)-induced chemotaxis of neutrophils.
생화학적/생리학적 작용
Tyrphostin 23 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain,.
특징 및 장점
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
Masaru Fujimoto et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(13), 6094-6099 (2010-03-17)
Endocytosis performs a wide range of functions in animals and plants. Clathrin-coated vesicle (CCV) formation is an initial step of endocytosis, and in animal cells is largely achieved by dynamins. However, little is known of its molecular mechanisms in plant
Janusz Ligęza et al.
Acta biochimica Polonica, 58(3), 391-396 (2011-09-03)
Autocrine growth factors produced by epithelial cells mediate the development and proliferation of neoplastic human prostate tissue. Various approaches have been used to down-regulate neoplastic growth of prostate cancer using natural flavonoids, soluble receptors, pseudo-ligands, monoclonal antibodies and tyrosine kinase
E Heim
Zeitschrift fur Psychosomatische Medizin und Psychoanalyse, 38(3), 207-226 (1992-01-01)
Stressors and health risks in medical professions are still largely ignored. A survey on different studies in nurses, students, doctors and dentists by this author is compared to results of other authors. Special attention is given to role-strain and health
Mikyung Yang et al.
American journal of physiology. Lung cellular and molecular physiology, 294(5), L1007-L1012 (2008-03-18)
We assessed the roles of the protein kinase C (PKC) and the tyrosine kinase (TK) signaling pathways in regulating capacitative calcium entry (CCE) in human pulmonary artery smooth muscle cells (PASMCs) and investigated the effects of intravenous anesthetics (midazolam, propofol
Doan-Trung Luu et al.
The Plant journal : for cell and molecular biology, 69(5), 894-905 (2011-11-05)
The constitutive cycling of plant plasma membrane (PM) proteins is an essential component of their function and regulation under resting or stress conditions. Transgenic Arabidopsis plants that express GFP fusions with AtPIP1;2 and AtPIP2;1, two prototypic PM aquaporins, were used
문서
Discover Bioactive Small Molecules for Kinase Phosphatase Biology
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