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Merck
모든 사진(1)

주요 문서

1324002

USP

Hydroquinone

United States Pharmacopeia (USP) Reference Standard

동의어(들):

1,4-Benzenediol, 1,4-Dihydroxybenzene, HQ

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About This Item

Linear Formula:
C6H4-1,4-(OH)2
CAS Number:
Molecular Weight:
110.11
Beilstein:
605970
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

pharmaceutical primary standard

vapor density

3.81 (vs air)

vapor pressure

1 mmHg ( 132 °C)

API family

hydroquinone

autoignition temp.

930 °F

제조업체/상표

USP

bp

285 °C (lit.)

mp

172-175 °C (lit.)

응용 분야

pharmaceutical (small molecule)

형식

neat

SMILES string

Oc1ccc(O)cc1

InChI

1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H

InChI key

QIGBRXMKCJKVMJ-UHFFFAOYSA-N

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일반 설명

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

Hydroquinone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Hydroquinone Cream
  • Hydroquinone Topical Solution

분석 메모

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

기타 정보

Sales restrictions may apply.

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

329.0 °F - closed cup

Flash Point (°C)

165 °C - closed cup


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시험 성적서(COA)

Lot/Batch Number

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Mekhala Chandra et al.
Acta dermato-venereologica, 92(3), 232-235 (2011-10-18)
Post-inflammatory hyperpigmentation after acne can be as troublesome as the acne itself. Hydroquinone, a tyrosinase inhibitor, in a 4% cream can be used safely twice daily for up to 6 months to treat post-inflammatory hyperpigmentation. The efficacy of this treatment
Jacob Levitt
Journal of the American Academy of Dermatology, 57(5), 854-872 (2007-05-01)
Recently, the US Food and Drug Administration proposed a ban on over-the-counter hydroquinone mainly on the basis of high absorption, reports of exogenous ochronosis in humans, and murine hepatic adenomas, renal adenomas, and leukemia with large doses over extended time
J J Nordlund et al.
Journal of the European Academy of Dermatology and Venereology : JEADV, 20(7), 781-787 (2006-08-11)
Hydroquinone is one of the most effective molecules for the treatment of hyperpigmentary disorders, with over 40 years of efficacy and safety data. Concerns over its safety have been raised because of the fact that it is a derivative of
A P DeCaprio
Critical reviews in toxicology, 29(3), 283-330 (1999-06-24)
Hydroquinone (HQ) is a high-volume commodity chemical used as a reducing agent, antioxidant, polymerization inhibitor, and chemical intermediate. It is also used in over-the-counter (OTC) drugs as an ingredient in skin lighteners and is a natural ingredient in many plant-derived
Changming Chen et al.
Plant physiology, 166(1), 370-383 (2014-07-23)
A seed's ability to properly germinate largely depends on its oxidative poise. The level of reactive oxygen species (ROS) in Arabidopsis (Arabidopsis thaliana) is controlled by a large gene network, which includes the gene coding for the hydrogen peroxide-scavenging enzyme

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