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Key Documents

122505

Sigma-Aldrich

2,3-Dihydroxypyridine

95%

Synonym(s):

2,3-Pyridinediol

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About This Item

Empirical Formula (Hill Notation):
C5H5NO2
CAS Number:
Molecular Weight:
111.10
Beilstein/REAXYS Number:
109848
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

95%

mp

245 °C (dec.) (lit.)

SMILES string

Oc1cccnc1O

InChI

1S/C5H5NO2/c7-4-2-1-3-6-5(4)8/h1-3,7H,(H,6,8)

Inchi Key

GGOZGYRTNQBSSA-UHFFFAOYSA-N

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Application

2,3-Dihydroxypyridine(DHP) was used in the synthesis of DHP loaded amberlite XAD-2 via azo coupler. It was used in the synthesis of new macromolecular chelators by loading DHP on cellulose via linkers -NH-CH2-CH2-NH-SO2-C6H4-N=N- and -SO2-C6H4-N=N.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lei Wang et al.
European journal of medicinal chemistry, 156, 680-691 (2018-07-23)
Human immunodeficiency virus (HIV) reverse transcriptase (RT)-associated ribonuclease H (RNase H) remains an unvalidated drug target. Reported HIV RNase H inhibitors generally lack significant antiviral activity. We report herein the design, synthesis, biochemical and antiviral evaluations of a new 6-biphenylmethyl
Jayakanth Kankanala et al.
European journal of medicinal chemistry, 141, 149-161 (2017-10-17)
Human immunodeficiency virus (HIV) reverse transcriptase (RT) associated ribonuclease H (RNase H) is the only HIV enzymatic function not targeted by current antiviral drugs. Although various chemotypes have been reported to inhibit HIV RNase H, few have shown significant antiviral
Lei Wang et al.
European journal of medicinal chemistry, 156, 652-665 (2018-07-23)
Human immunodeficiency virus (HIV) reverse transcriptase (RT) associated ribonuclease H (RNase H) remains the only virally encoded enzymatic function not targeted by current drugs. Although a few chemotypes have been reported to inhibit HIV RNase H in biochemical assays, their
2, 3-Dihydroxypyridine loaded amberlite XAD-2 (AXAD-2-DHP): preparation, sorption-desorption equilibria with metal ions, and applications in quantitative metal ion enrichment from water, milk and vitamin samples.
Venkatesh G, et al.
Microchimica Acta, 149(3-4), 213-221 (2005)
The first mu(6)-peroxide transition-metal complex: [Ni(8)(L)(12)(O(2))](2+).
Emma J Brown et al.
Angewandte Chemie (International ed. in English), 44(9), 1392-1395 (2005-01-05)

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