133337
4-Acetamidobenzoic acid
98%
Synonym(s):
N-Acetyl-PABA
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About This Item
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Quality Level
assay
98%
form
powder
reaction suitability
reaction type: solution phase peptide synthesis
mp
259-262 °C (dec.) (lit.)
application(s)
peptide synthesis
SMILES string
CC(=O)Nc1ccc(cc1)C(O)=O
InChI
1S/C9H9NO3/c1-6(11)10-8-4-2-7(3-5-8)9(12)13/h2-5H,1H3,(H,10,11)(H,12,13)
InChI key
QCXJEYYXVJIFCE-UHFFFAOYSA-N
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Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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In humans, polymorphic N-acetyltransferases NAT1 and NAT2 are important enzymes that metabolize endogenous and exogenous compounds, including drugs. These enzymes exhibit considerable inter-individual variability in humans. The cynomolgus macaque is a nonhuman primate species that is widely used in drug
Bioorganic & medicinal chemistry, 15(5), 2106-2119 (2007-01-16)
Benzoic acid and pyridine derivatives inhibit recombinant trans-sialidase from Trypanosoma cruzi with I50 values between 0.4 and 1mM. The best compounds, 4-acetylamino-3-hydroxymethylbenzoic acid and 5-acetylamino-6-aminopyridine-2-carboxylic acid, provide new leads to inhibitors not containing the synthetically complex sialic acid structure. The
Journal of pharmaceutical and biomedical analysis, 43(4), 1430-1436 (2006-11-23)
p-Aminobenzoic acid (PABA) and its metabolites (p-aminohippuric acid, p-acetamidobenzoic acid, and p-acetamidohippuric acid) were detected using high-performance liquid chromatography with an electrochemical (carbon paste) detector (HPLC-ECD). For direct current (dc) mode, with the current at a constant potential, and measurements
Antimicrobial agents and chemotherapy, 37(6), 1227-1231 (1993-06-01)
Isoprinosine has been reported to decrease progression to AIDS, primarily by preventing Pneumocystis carinii pneumonia (PCP), in human immunodeficiency virus-infected patients, but the mechanism of action is unknown. para-Acetamidobenzoic acid (PAcBA), one component of isoprinosine, is structurally related to para-aminobenzoic
Clinical biochemistry, 28(5), 531-540 (1995-10-01)
To evaluate glycine conjugation of para-aminobenzoic acid (PABA) to the hippurated metabolites, para-aminohippuric acid (PAHA), and para-acetamidohippuric acid (PAAHA) as a quantitative liver function test in patients with liver disease. Serum concentrations of PABA and metabolites were measured by high
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