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Sigma-Aldrich

2,6-Difluorobenzaldehyde

98%

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Linear Formula:
F2C6H3CHO
CAS Number:
Molecular Weight:
142.10
Beilstein:
1935273
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

form

liquid

refractive index

n20/D 1.502 (lit.)

bp

82-84 °C/15 mmHg (lit.)

mp

15-17 °C (lit.)

density

1.317 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

Fc1cccc(F)c1C=O

InChI

1S/C7H4F2O/c8-6-2-1-3-7(9)5(6)4-10/h1-4H

InChI key

SOWRUJSGHKNOKN-UHFFFAOYSA-N

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1 of 4

This Item
728985706957132497
2,6-Dichloropyrazine 98%

Sigma-Aldrich

132497

2,6-Dichloropyrazine

form

liquid

form

solid

form

solid

form

solid

refractive index

n20/D 1.502 (lit.)

refractive index

-

refractive index

-

refractive index

-

bp

82-84 °C/15 mmHg (lit.)

bp

-

bp

-

bp

-

mp

15-17 °C (lit.)

mp

68-73 °C

mp

76-81 °C

mp

55-58 °C (lit.)

density

1.317 g/mL at 25 °C (lit.)

density

-

density

-

density

-

Application

2,6-Difluorobenzaldehyde can be used as a reactant to synthesize:
  • 5-Cyano-6-(2,6-difluorophenyl)-5,6-dihydro-2-thiouracil via one-pot cyclocondensation reaction with ethyl cyanoacetate and thiourea.
  • 1-(2,6-Difluorobenzyl)-2-(2,6-difluorophenyl)-benzimidazole by reacting with 1,2-phenylenediamine in the presence of a catalytic amount of p-toluenesulfonic acid.
  • (3E)-4-(2,6-Difluorophenyl)-3-buten-2-one by Wittig olefination reaction with acetylmethylidenetriphenyl phosphorane.
  • Methyl 4-fluorobenzo[b]thiophene-2-carboxylate by treating with methyl thioglycolate in the presence of K2CO3.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1C

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

180.5 °F - closed cup

Flash Point(C)

82.5 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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