MilliporeSigma
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457620

Sigma-Aldrich

Polyglycolide

inherent viscosity 1.4dL/g

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Synonym(s):
PGA, Poly(glycolic acid)
Linear Formula:
(C2H4O3)n
CAS Number:
26124-68-5
MDL number:
MFCD00148011
PubChem Substance ID:
24869373
NACRES:
NA.23

Quality Level

100

form

solid

degradation timeframe

6-12 months

inherent viscosity

1.1-1.7 dL/g, 0.1 % (w/v) in hexafluoroisopropanol(25 °C)

transition temp

Tm 220-230 °C

solubility

hexafluoroisopropanol: soluble

density

1.53 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

OCC(O)=O

InChI

1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)

InChI key

AEMRFAOFKBGASW-UHFFFAOYSA-N

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Polyglycolide inherent viscosity 1.4dL/g

Sigma-Aldrich

457620

Polyglycolide

Polycaprolactone viscosity 1.7 dL/g 

Sigma-Aldrich

900820

Polycaprolactone

Polycaprolactone viscosity 1.2 dL/g 

Sigma-Aldrich

900822

Polycaprolactone

Polycaprolactone viscosity 0.40 dL/g 

Sigma-Aldrich

900825

Polycaprolactone

form

solid

form

chunks

form

chunks

form

chunks

transition temp

Tm 220-230 °C

transition temp

-

transition temp

-

transition temp

-

density

1.53 g/mL at 25 °C (lit.)

density

-

density

-

density

-

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

degradation timeframe

6-12 months

degradation timeframe

-

degradation timeframe

-

degradation timeframe

-

inherent viscosity

1.1-1.7 dL/g, 0.1 % (w/v) in hexafluoroisopropanol(25 °C)

inherent viscosity

1.5-1.9 dL/g

inherent viscosity

1.0-1.3 dL/g

inherent viscosity

0.35-0.43 dL/g

General description

Biodegradable and biocompatible PGA could be potentially useful for bone regeneration. High molecular weight polyglycolide (PGA) can be prepared by ring opening polymerization of diglycolide in the presence of diphenyl bismuth bromide.

Application

Polyglycolide (PGA) along with polylactide may be used to prepare a biodegradable copolymer to be used as implantations. Fabrication of biopolymer/carbon nanotube composite has been reported using PGA fiber as one of the constituents of the composite. Modified porous PGA scaffolds has been fabricated.
medical device

Physical properties

Biodegradable polymer

Preparation Note

To achieve solubility in hexafluoroisopropanol, melt crystalline product and quench with liquid nitrogen to change material to amorphous form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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