524417
3,5-Dinitro-o-toluamide
98%
Synonym(s):
2-Methyl-3,5-dinitrobenzamide
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assay
98%
mp
170-180 °C (lit.)
functional group
amide
nitro
SMILES string
Cc1c(cc(cc1[N+]([O-])=O)[N+]([O-])=O)C(N)=O
InChI
1S/C8H7N3O5/c1-4-6(8(9)12)2-5(10(13)14)3-7(4)11(15)16/h2-3H,1H3,(H2,9,12)
InChI key
ZEFNOZRLAWVAQF-UHFFFAOYSA-N
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General description
Water solubility of 3,5-Dinitro-o-toluamide (3,5-DNoTAME) is 447.5mg/L. It affords 3-amino-5-nitro-o-toluamide, via biological reduction. 3,5-DNoTAME also forms colored complexes on reaction with various diamines and organic solvents.
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Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk_germany
WGK 2
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Parasitology, 78(1), 33-40 (1979-02-01)
N,N'-bis (3,4 ditrifluoromethylphenyl) methylmalonamide (Sch 18545) completely controlled a mild Eimeria necatrix infection at 50, 40 or 30 p.p.m. in the diet, and controlled E. tenella infections at 50 and 40 p.p.m. Slight oocyst passage was observed at each E.
Parasitology, 75(2), 155-164 (1977-10-01)
Chicks infected with the Weybridge strains of Eimeria maxima and E. acervulina were not protected by the normal levels of amprolium, but the sporulation of the oocysts was inhibited. With higher drug concentrations, fewer oocysts were produced. E brunetti was
Feed Additive Residues, Isolation and Identification of Amino-nitro-o-toluamide Formed by Biological Reduction of 3, 5-Dinitro-o-tuamide.
Journal of Agricultural and Food Chemistry, 11(3), 257-260 (1963)
Anticoccidial drugs: effects on infectivity and survival intracellularly of Eimeria tenella sporozoites.
Experimental parasitology, 40(3), 314-319 (1976-12-01)
Mutation research, 77(1), 21-30 (1980-01-01)
18 feed additives were tested for DNA-modifying effects by the repair test named "rec-assay" with Bacillus subtillis H17 (rec+) and M45 (rec-), and for mutagenicity with Escherichia coli WP2 hcr and 5 Salmonella typhimurium tester strains with the use of
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