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568864

Sigma-Aldrich

Fluorescein O-methacrylate

95%

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Synonym(s):
3′-Methacryloxyspirobenzo[c]-furan[1,9’]xanthen-3-one, Methacryloyloxy fluorescein
Empirical Formula (Hill Notation):
C24H16O6
CAS Number:
Molecular Weight:
400.38
MDL number:
PubChem Substance ID:
NACRES:
NA.23

Quality Level

assay

95%

form

solid

mp

227-232 °C (lit.)

λmax

490 nm

storage temp.

2-8°C

SMILES string

CC(=C)C(=O)Oc1ccc2c(Oc3cc(O)ccc3C24OC(=O)c5ccccc45)c1

InChI

1S/C24H16O6/c1-13(2)22(26)28-15-8-10-19-21(12-15)29-20-11-14(25)7-9-18(20)24(19)17-6-4-3-5-16(17)23(27)30-24/h3-12,25H,1H2,2H3

InChI key

YMHPNLUYVDEYCI-UHFFFAOYSA-N

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This Item
F6377F7250F3651
Fluorescein O-methacrylate 95%

568864

Fluorescein O-methacrylate

Fluorescein sodium salt used as fluorescent tracer

F6377

Fluorescein sodium salt

Fluorescein isothiocyanate isomer I suitable for protein labeling, ≥90% (HPLC), powder

F7250

Fluorescein isothiocyanate isomer I

Fluorescein 5(6)-isothiocyanate ≥90% (HPLC)

F3651

Fluorescein 5(6)-isothiocyanate

assay

95%

assay

-

assay

≥90% (HPLC)

assay

≥90% (HPLC)

storage temp.

2-8°C

storage temp.

room temp

storage temp.

2-8°C

storage temp.

2-8°C

λmax

490 nm

λmax

-

λmax

-

λmax

-

mp

227-232 °C (lit.)

mp

>300 °C

mp

>360 °C (lit.)

mp

-

General description

Fluorescein O-methacrylate is a pH sensitive dye with a fluorescent monomer. It can be characterized by an excitation spectra at 490 nm and an emission spectra at 520 nm. It has fluorescein that acts as an indicator with the least negative charges. Its properties include biocompatibility, non-toxicity and good dispersion in aqueous solution.

Application

Fluorescein O-methacrylate can be used as a marker that can be incorporated into the nanoparticle complexes for biological applications. It forms environmentally responsive materials that can be used as probes for cellular imaging.
Fluorescent monomer

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Saha A, et al.
The Journal of Physical Chemistry C, 113(43), 18492-18498 (2009)
Disposable fluorescence optical pH sensor for near neutral solutions
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Zhenhua Li et al.
Nanoscale, 9(40), 15407-15415 (2017-10-05)
Protein modified functional surfaces have been applied extensively in the field of biomaterials and medicine. Regulation of the amount and activity of proteins on the material surface is always a challenge and a key research issue. A multifunctional micro/nano-composite based
Synthesis and characterization of multifunctional Fe3O4/poly (fluorescein O-methacrylate) core/shell nanoparticles
Govindaiah P, et al.
Journal of Colloid and Interface Science, 379(1), 27-32 (2012)
Aydan Dag et al.
Biomacromolecules, 20(8), 2962-2972 (2019-07-18)
An important requirement to decrease the side effects of chemotherapy drugs is to develop nanocarriers with precise biological functions. In this work, a set of glyconanoparticles was prepared via self-assembly of amphiphilic glycoblock copolymers for the targeted delivery of a

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