Skip to Content
MilliporeSigma
All Photos(3)

Key Documents

View All Documentation

693863

Sigma-Aldrich

Hydroxyapatite

nanopowder, <200 nm particle size (BET), contains 5 wt. % silica as dopant, synthetic

Synonym(s):

Calcium phosphate tribasic, Si-HAp, Calcium hydroxyphosphate, HAp, Hydroxylapatite, Tribasic calcium phosphate

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Linear Formula:
[Ca5(OH)(PO4)3]x
CAS Number:
12167-74-7
Molecular Weight:
502.31
MDL number:
MFCD00010904
UNSPSC Code:
12352302
PubChem Substance ID:
329761628
NACRES:
NA.23

Quality Level

100

form

nanopowder
solid

contains

5 wt. % silica as dopant

surface area

10-15 m2/g , typical

particle size

<200 nm (BET)

mp

1100 °C (lit.)

bulk density

2‑6 g/cm3

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

Looking for similar products? Visit Product Comparison Guide

Application

Si-substituted hydroxyapatite (Si-HAp) nanopowder can be incorporated in biodegradable polymer composites or deposited on biocompatible surfaces similar to pure HAp nanopowder (cat. no. 677418). Biological activity of HAp was shown to be enhanced by substitution of silicon ions into a fraction of HAp lattice phosphate sites.

Legal Information

Product of Engi-Mat Co.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Lee, J. -H.; Lee, K. S. et al.
Key Engineering Materials, 254-256, 135-135 (2004)
Shiori Doi et al.
Scientific reports, 6, 38021-38021 (2016-12-03)
Piperonal-catabolizing microorganisms were isolated from soil, the one (strain CT39-3) exhibiting the highest activity being identified as Burkholderia sp. The piperonal-converting enzyme involved in the initial step of piperonal metabolism was purified from strain CT39-3. Gene cloning of the enzyme
S R Kim et al.
Biomaterials, 24(8), 1389-1398 (2003-01-16)
Si, Mg-substituted hydroxyapatites, alone and co-substituted, have been prepared to obtain biomaterials having an improved biocompatibility. From FT-IR, XRD and ICP analyses, it was confirmed that single phases of hydroxyapatite substituted by Si alone or co-substituted by Si, Mg. The
Influence of temperature, ripening time and calcination on the morphology and crystallinity of hydroxyapatite nanoparticles.
Pang YX, et al.
J. Eur. Ceram. Soc., 23(10), 1697-1704 (2003)
Hydroxyapatite nanoparticles: a review of preparation methodologies
Ferraz MP, et al.
Journal of Applied Biomaterials & Biomechanics : JABB, 2(2), 74-80 (2004)
View All Related Papers

Articles

Nanomaterials for Biomedical Applications

Nanoparticles can be used for applications such as growing cells for tissue engineering, nanocomposites used in orthopedics, and miniaturized sensors for DNA, pathogens, and chemicals.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service