900858

2-(Prop-2-yn-1-yloxy)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoic acid

≥95%

• Synonym(s): Carboxyl diazirine alkyne, Probe building block
• Empirical Formula (Hill Notation): C₁₂H₇F₃N₂O₃
• CAS Number: 2187374-12-3
• Molecular Weight: 284.19
• UNSPSC Code: 12352106
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: ≥95%
• form: powder
• reaction suitability: reaction type: click chemistry
• storage temp.: −20°C
• SMILES string: C#CCOC1=CC(C2(N=N2)C(F)(F)F)=CC=C1C(O)=O

Description

Application

2-(Prop-2-yn-1-yloxy)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Other Notes

Technology Spotlight: Trifunctional Probe Building Blocks

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable