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A7256

Sigma-Aldrich

DL-Norepinephrine hydrochloride

crystalline, ≥97% (TLC)

Synonym(s):

(±)-1-(3,4-Dihydroxyphenyl)-2-aminoethanol hydrochloride, (±)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol hydrochloride, DL-Arterenol hydrochloride, DL-Noradrenaline hydrochloride

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About This Item

Linear Formula:
(HO)2C6H3CH(OH)CH2NH2 · HCl
CAS Number:
55-27-6
Molecular Weight:
205.64
Beilstein/REAXYS Number:
3707003
EC Number:
200-229-8
MDL number:
MFCD00012880
UNSPSC Code:
12352100
PubChem Substance ID:
57653879
NACRES:
NA.22

Quality Level

200

assay

≥97% (TLC)

form

crystalline

color

off-white to tan

solubility

water: soluble 50 mg/mL, clear to slightly hazy, faintly yellow to brownish-yellow

storage temp.

−20°C

SMILES string

NCC(C1=CC(O)=C(C=C1)O)O.Cl

InChI

1S/C8H11NO3.ClH/c9-4-8(12)5-1-2-6(10)7(11)3-5;/h1-3,8,10-12H,4,9H2;1H

InChI key

FQTFHMSZCSUVEU-UHFFFAOYSA-N

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General description

DL-Norepinephrine hydrochloride is an adrenergic drug.

Application

DL-Norepinephrine hydrochloride is suitable adrenergic drug used in the following studies:
  • To investigate the effects of adrenergic drugs on lantern of larval fly.
  • To evaluate the ability of α-adrenergic stimulation in the presence of elevated calcium levels to induce delayed after depolarizations and triggered activity in Purkinje fibers isolated from cat hearts.
  • Simultaneous reduction and surface functionalization of graphene oxide by a one-step poly(norepinephrine) functionalization.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Simultaneous Reduction and Surface Functionalization of Graphene Oxide by Mussel-Inspired Chemistry.
Kang SM, et al.
Advances in Functional Materials, 21(1), 108-112 (2011)
Effect of adrenergic drugs on the lantern of the larval Photuris firefly.
A D Carlson
The Journal of experimental biology, 48(2), 381-387 (1968-04-01)
Yining Chen et al.
Journal of neurophysiology, 125(6), 2397-2407 (2021-05-13)
Sensory learning during critical periods in development has lasting effects on behavior. Neuromodulators like dopamine and norepinephrine (NE) have been implicated in various forms of sensory learning, but little is known about their contribution to sensory learning during critical periods.
S Kimura et al.
Circulation, 70(6), 1074-1082 (1984-12-01)
We studied the ability of alpha-adrenergic stimulation to induce delayed afterdepolarizations and triggered activity in Purkinje fibers from cat hearts in the presence of an elevated Ca++ concentration. Delayed afterdepolarizations could not be induced at drive cycle lengths of 200
Alexis N Orr et al.
International journal of molecular sciences, 22(5) (2021-04-04)
Transglutaminases (TGs) are crosslinking enzymes best known for their vascular remodeling in hypertension. They require calcium to form an isopeptide bond, connecting a glutamine to a protein bound lysine residue or a free amine donor such as norepinephrine (NE) or
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