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W291706

Sigma-Aldrich

Polysorbate 80

FG

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Synonym(s):
TWEEN® 80, POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80
CAS Number:
9005-65-6
FEMA Number:
2917
MDL number:
MFCD00082107
E Number:
E 433
NACRES:
NA.21

biological source

palm oil
synthetic

Quality Level

400

grade

FG
Halal
Kosher

reg. compliance

EU Regulation 1333/2008 & 178/2002
FDA 21 CFR 172.515
FDA 21 CFR 172.836
FDA 21 CFR 172.838
FDA 21 CFR 172.840
FDA 21 CFR 172.842

vapor pressure

<1 mmHg ( 20 °C)

refractive index

n20/D 1.472 (lit.)

density

1.064 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

corn

Organoleptic

alcohol

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

InChI key

RGPBUVUVZKQNHD-MDZDMXLPSA-N

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1 of 4

This Item
5992415479691.37171
Polysorbate 80 FG

Sigma-Aldrich

W291706

Polysorbate 80

Polysorbate 80 tested according to Ph. Eur.

Sigma-Aldrich

59924

Polysorbate 80

Polysorbate 80 United States Pharmacopeia (USP) Reference Standard

USP

1547969

Polysorbate 80

Polysorbate 80 high purity, EMPROVE&#174; EXPERT, Ph. Eur., ChP, JP, NF

SAFC

1.37171

Polysorbate 80

grade

FG, Halal, Kosher

grade

-

grade

-

grade

GDP, GMP, Halal, Kosher

refractive index

n20/D 1.472 (lit.)

refractive index

n20/D 1.472 (lit.)

refractive index

-

refractive index

-

density

1.064 g/mL at 25 °C (lit.)

density

1.064 g/mL at 25 °C (lit.)

density

-

density

1.07 g/cm3 at 25 °C

documentation

see Safety & Documentation for available documents

documentation

-

documentation

-

documentation

-

food allergen

corn

food allergen

-

food allergen

-

food allergen

-

General description

Polysorbate 80 (TWEEN® 80) is a polyethylene sorbitol ester.

Application

Polysorbate 80 (TWEEN® 80), a hydrophilic non-ionic surfactant, is widely employed as a surfactant and solubilizing agent in food and cosmetic industries.

Legal Information

TWEEN is a registered trademark of Croda International PLC

related product

Product No.
Description
Pricing

07475

Timestrip® Food, null

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Hongjian Zhang et al.
Archives of pharmacal research, 26(9), 768-772 (2003-10-17)
Tween 80 (Polysorbate 80) is a hydrophilic nonionic surfactant commonly used as an ingredient in dosing vehicles for pre-clinical in vivo studies (e.g., pharmacokinetic studies, etc.). Tween 80 increased apical to basolateral permeability of digoxin in Caco-2 cells suggesting that
Stability characterization of a polysorbate 80-dimethyl trisulfide formulation, a cyanide antidote candidate.
Bartling CM, et al.
Drugs in R&D, 16(1), 109-127 (2016)
Use of Polysorbate 80 (Tween 80) as a phase-transfer catalyst.
Thoman CJ, et al.
The Journal of Organic Chemistry, 54(18), 4476-4478 (1989)
Tatiana Beldarrain-Iznaga et al.
Food research international (Ottawa, Ont.), 141, 110136-110136 (2021-03-02)
To provide their health effect, probiotics need to maintain their viability, adhere to the intestinal epithelium, and colonize it without losing their probiotic properties. In the present study, Lactobacillus casei was encapsulated in a double emulsion and then coated with
Asher Preska Steinberg et al.
Biomacromolecules, 20(7), 2675-2683 (2019-06-28)
Systems consisting of a polyelectrolyte solution in contact with a cross-linked polyelectrolyte network are ubiquitous (e.g., biofilms, drug-delivering hydrogels, and mammalian extracellular matrices), yet the underlying physics governing these interactions is not well understood. Here, we find that carboxymethyl cellulose

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