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44112

Sigma-Aldrich

Polysorbate 20

tested according to Ph. Eur.

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Synonym(s):
Polysorbatum 20
CAS Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.21

agency

USP/NF
tested according to Ph. Eur.

Quality Level

description

non-ionic

form

liquid

mol wt

~1228 g/mol

CMC

0.06

transition temp

cloud point 76 °C

HLB

16.7

application(s)

pharmaceutical (small molecule)

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

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Application


  • Evaluating a Modified High Purity Polysorbate 20 Designed to Reduce the Risk of Free Fatty Acid Particle Formation.: The research evaluates a modified high purity form of Polysorbate 20, designed to mitigate the formation of free fatty acid particles. This modification potentially enhances the stability and safety of biopharmaceutical formulations (Doshi et al., 2021).

wgk_germany

WGK 1

ppe

Eyeshields, Gloves


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Gunasekaran Dhandapani et al.
mAbs, 11(3), 583-592 (2019-01-09)
We introduce a new concept and potentially general platform for antibody (Ab) purification that does not rely on chromatography or specific ligands (e.g., Protein A); rather, it makes use of detergent aggregates capable of efficiently capturing Ab while rejecting hydrophilic

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