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Key Documents

P6585

Sigma-Aldrich

TWEEN® 20

Low-peroxide; Low-carbonyls

Synonym(s):

Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12161900
NACRES:
NA.21

Quality Level

description

non-ionic

form

viscous liquid

mol wt

~1228

contains

BHT as antioxidant

impurities

≤0.5 μmol/g Peroxides
≤1.0 μmol/g Carbonyls
≤3.0% water

refractive index

n20/D 1.468 (lit.)

CMC

0.06 mM (20-25°C)

transition temp

cloud point 76 °C

density

1.095 g/mL at 25 °C (lit.)
1.1 g/cm3 at 25 °C (lit.)

HLB

16.7

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCC(=O)OCCOCC(C1C(C(CO1)OCCO)OCCO)OCCO

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

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General description

Tween®20 is a polyoxyethylene sorbitol ester that belongs to the polysorbate family. It is a nonionic detergent having a molecular weight of 1,225 daltons, assuming 20 ethylene oxide units, 1 sorbitol, and 1 lauric acid as the primary fatty acid. The ethylene oxide subunits are responsible for the hydrophilic nature of the surfactant, while the hydrocarbon chains provide the hydrophobic environment. Sorbitol forms the backbone ring to which the ethylene oxide polymers are attached.

Application

Tween 20 has been used along with PBS to wash plates in ELISA technique.
Non-ionic detergent

Preparation Note

Purified to remove peroxides and aldehydes

Legal Information

TWEEN is a registered trademark of Croda International PLC

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

527.0 °F - Pensky-Martens closed cup

flash_point_c

275 °C - Pensky-Martens closed cup

ppe

Eyeshields, Gloves


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