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Sigma-Aldrich

Sodium dodecyl sulfate

for biochemistry 10% in H₂O

Synonym(s):
Dodecyl sulfate sodium salt, SDS, Lauryl sulfate sodium salt, Dodecyl sodium sulfate

Quality Level

form

liquid

pH

9 (20 °C in H2O)

density

1.012 g/cm3 at 20 °C

storage temp.

15-25°C

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This Item
75746RDD021L5750
Sodium dodecyl sulfate ≥99.0% (GC), dust-free pellets

Sigma-Aldrich

75746

Sodium dodecyl sulfate

Sodium dodecyl sulfate 92.5-100.5% based on total alkyl sulfate content basis

Sigma-Aldrich

L5750

Sodium dodecyl sulfate

density

1.012 g/cm3 at 20 °C

density

-

density

-

density

-

storage temp.

15-25°C

storage temp.

-

storage temp.

-

storage temp.

-

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

200

pH

9 (20 °C in H2O)

pH

-

pH

-

pH

-

General description

Dodecyl sulfate sodium or sodium dodecyl sulfate (SDS) is an ionic detergent comprising a polar sulfate head group and a hydrophobic 12-carbon chain.

Biochem/physiol Actions

Dodecyl sulfate sodium or sodium dodecyl sulfate (SDS) combines effectively with the positively charged and hydrophobic residues of proteins using sulfate groups and alkyl chains. This detergent is very valuable in the field of structural biology and protein folding/unfolding studies. SDS can initiate the generation of α-helices in a protein structure. It stimulates cooperative unfolding in proteins like bovine serum albumin (BSA), β-lactoglobulin, α-lactalbumin, and hen egg-white lysozyme structures at elevated concentrations.

Analysis Note

Assay (two-phase titration): 9.8 - 10.2 %

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Protocols

Cell Lysis and Protein Extraction for Western Blotting

Protocol for sample preparation for cell lysis and efficient protein extraction from cultured tissues and cells for subsequent Western blotting.

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