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MilliporeSigma

1.06431

SAFC

tri-Sodium citrate 5,5-hydrate

EMPROVE® ESSENTIAL, E 331

Pharma Manufacturing

Synonym(s):

tri-Sodium citrate 5,5-hydrate

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1 KIT
$1,480.00

$1,480.00


Estimated to ship onMay 25, 2025


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1 KIT
$1,480.00

About This Item

Empirical Formula (Hill Notation):
C6H5Na3O7 · 5.5H2O
CAS Number:
Molecular Weight:
357.15
MDL number:
UNSPSC Code:
12352107
E Number:
E331
EC Index Number:
200-675-3

grade:
for analytical purposes
form:
solid
solubility:
920 g/L

$1,480.00


Estimated to ship onMay 25, 2025


Request a Bulk Order

grade

for analytical purposes

Quality Level

description

FU VIII grade

product line

EMPROVE® ESSENTIAL

form

solid

pH

7.5-9.0 (20 °C, 50 g/L in H2O)

mp

>150 °C (anhydrous)

solubility

920 g/L

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

2-30°C

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This Item
1.003181.0151413-1740
Quality Level

300

Quality Level

100

Quality Level

100

Quality Level

-

form

liquid

form

liquid

form

liquid

form

liquid

pH

<1 (20 °C in H2O)

pH

<1 (20 °C, 300 g/L in H2O)

pH

<1 (20 °C, 300 g/L in H2O)

pH

-

storage temp.

2-30°C

storage temp.

15-25°C

storage temp.

2-30°C

storage temp.

-

impurities

≤0.01 ppm As (Arsenic), ≤0.010 ppm Co (Cobalt), ≤0.010 ppm Mn (Manganese), ≤0.010 ppm V (Vanadium), ≤0.020 ppm Be (Beryllium), ≤0.020 ppm Cu (Copper), ≤0.020 ppm Ni (Nickel), ≤0.050 ppm Al (Aluminium), ≤0.050 ppm Tl (Thallium), ≤0.100 ppm Bi (Bismuth), ≤0.100 ppm Mg (Magnesium), ≤0.100 ppm Zr (Zirconium), ≤0.5 ppm Free chlorine (Cl), ≤0.500 ppm Na (Sodium), ≤1 ppm Sulfate (SO4), ≤50 ppm Bromide (Br), ≤0.010 ppm Cd (Cadmium), ≤0.010 ppm Sr (Strontium), ≤0.020 ppm Cr (Chromium), ≤0.020 ppm Pb (Lead), ≤0.050 ppm Zn (Zinc), ≤0.100 ppm Ti (Titanium), ≤0.500 ppm Ca (Calcium), ≤1 ppm Sulfite (SO3), ≤0.010 ppm Li (Lithium), ≤0.020 ppm Mo (Molybdenum), ≤0.100 ppm K (Potassium), ≤1 ppm NH4 (Ammonium), ≤0.020 ppm Ba (Barium), ≤0.200 ppm Fe (Iron), ≤0.050 ppm Ge (Germanium)

impurities

-

impurities

-

impurities

-

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Tri-sodium citrate 5,5-hydrate is widely used in pharmaceutical formulations, typically as pH adjuster and buffer agent.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


What is the Emprove® Program?

The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials. Four document types are included with an Emprove® Program subscription:

Material Qualification Dossier

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Quality Management Dossier (Open Access)

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Operational Excellence Dossier

Available by subscription or for a fee

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Why are these documents unavailable?
Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

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