117105

Adenosine 5′-diphosphate monopotassium salt dihydrate

M.W. 501.3 (dihydrate).

• Synonym(s): ADP, K, Adenosine 5-Diphosphate, Potassium Salt, ADP
• Empirical Formula (Hill Notation): C₁₀H₁₄KN₅O₁₀P₂ · 2H₂O
• CAS Number: 72696-48-1
• Molecular Weight: 501.32
• MDL number: MFCD00066472
• UNSPSC Code: 12352208
• NACRES: NA.51

Properties

• Quality Level: 100
• assay: ≥98% dry basis (enzymatic)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic)
• impurities: ≤0.2% ATP (enzymatic); ≤1% AMP
• color: white
• solubility: water: 50 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: [O-]P(OP(OC[C@H]([C@@H](O)[C@H]1O)O[C@H]1N2C3=C(N=C2)C(N)=NC=N3)(O)=O)(O)=O.[K+]
• InChI: 1S/C10H15N5O10P2.K/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1
• InChI key: ZNCWUOPIJTUALR-MCDZGGTQSA-M

Description

Application

• Elevated plasma levels of factor VIII enhance arterial thrombus formation on erosive smooth muscle cell-rich neointima but not normal intima in rabbits.: This study explores the effects of elevated plasma levels of factor VIII on arterial thrombus formation, a crucial aspect in understanding vascular diseases and developing therapeutic interventions, where Adenosine 5 prime-diphosphate (ADP) is used for the analysis of platelet aggregation and plays a pivotal role in thrombosis and hemostasis (Sugita et al., 2024).


• An energy-conserving reaction in amino acid metabolism catalyzed by arginine synthetase.: This research highlights the biochemical role of ADP in facilitating energy-conserving reactions in amino acid metabolism, particularly through the catalytic action of arginine synthetase, underscoring its potential in metabolic engineering and therapeutic applications (Michimori et al., 2024).


• Transcriptome analysis of cultured human vascular endothelial cells after gamma-ray irradiation and correlation analysis with ATP, ADP, and adenosine as secondary soluble factors.: ADP is used as a cell culture component to study its impact alongside other nucleotides in modulating cellular responses to radiation, providing insights into cellular defense mechanisms and the potential for developing radioprotective strategies (Fujie et al., 2024).

Warning

Toxicity: Standard Handling (A)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable