Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

1.37136

SAFC

Tetrahydrofuran

EMPROVE® ESSENTIAL

Pharma Manufacturing

Synonym(s):

Tetrahydrofuran, Butylene oxide, Oxolane, Tetramethylene oxide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C4H8O
CAS Number:
109-99-9
Molecular Weight:
72.11
Beilstein/REAXYS Number:
102391
MDL number:
MFCD00005356
UNSPSC Code:
12352005
Pricing and availability is not currently available.

vapor density

2.5 (vs air)

Quality Level

500

vapor pressure

114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

product line

EMPROVE® ESSENTIAL

assay

≥99.8% (GC)

form

liquid

autoignition temp.

610 °F

expl. lim.

1.8-11.8 %

technique(s)

API processing | polymorph screening: suitable

refractive index

n20/D 1.407 (lit.)

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

We offer a range of high quality critical raw materials, solvents and reagents plus the documentation and expertise to meet stringent regulatory requirements. In addition to our comprehensive portfolio, we also offer custom manufacturing services to meet your exact needs. As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Tetrahydrofuran is a versatile organic solvent for API synthesis, as a pre-cursor to polymers and it is used for several extended applications during drug manufacturing. The performance of the processes increases with the usage of Tetrahydrofuran in certain API′s than other available solvents. Tetrahydrofuran Emprove® Essential is manufactured according to GMP guidelines and is suitable for pharmaceutical applications.

Linkage

Emprove Documentation

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2

supp_hazards

EUH019

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

-6.2 °F - closed cup

flash_point_c

-21.2 °C - closed cup

What is the Emprove® Program?

The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials. Four document types are included with an Emprove® Program subscription:

Material Qualification Dossier

Free of charge - Sign in to download

Quality Management Dossier (Open Access)

Free of charge - Sign in to download

Operational Excellence Dossier

Available by subscription or for a fee

Learn more about the benefits an Emprove® Program subscription can provide
Why are these documents unavailable?
Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service