1.16224

Sodium chloride

EMPROVE^® EXPERT, Ph. Eur., BP, JP, USP

• Synonym(s): Halite, NaCl
• Linear Formula: NaCl
• CAS Number: 7647-14-5
• Molecular Weight: 58.44
• Beilstein/REAXYS Number: 3534976
• MDL number: MFCD00003477
• UNSPSC Code: 12352302
• EC Index Number: 231-598-3

Properties

• agency: BP; JP; Ph. Eur.; USP
• Quality Level: 500
• vapor pressure: 1.3 hPa ( 865 °C)
• product line: EMPROVE^® EXPERT
• form: solid
• pH: 4.5-7.0 (20 °C, 100 g/L in H₂O)
• bp: 1461 °C/1013 hPa
• mp: 801 °C (lit.)
• solubility: 358 g/L
• density: 2.17 g/cm³ at 20 °C
• application(s): liquid formulation; ophthalmics; parenterals; pharma/biopharma processes; pharmaceutical
• storage temp.: 2-30°C
• SMILES string: [Na+].[Cl-]
• InChI: 1S/ClH.Na/h1H;/q;+1/p-1
• InChI key: FAPWRFPIFSIZLT-UHFFFAOYSA-M

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sodium chloride is a mineral salt with broad range of applications in pharmaceutical formulations. It is typically used as an osmotic agent in liquid dosage forms e.g. for preparation of isotonic formulations, as bulking or coating agent for solid dosage forms, as well as for semi-solid dosage forms like creams.
Due to its low microbial and endotoxin limits, Sodium chloride Emprove^® Expert is especially suitable for high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable