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341573

Sigma-Aldrich

Fibrinogen, Bovine Plasma

Fibrinogen, CAS 9001-32-5, is a soluble plasma glycoprotein that is synthesized in the hepatic parenchymal cells. Contains mpre than 95% clottable protein.

Synonym(s):

Fibrinogen, Bovine Plasma, Coagulation Factor I

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About This Item

CAS Number:
UNSPSC Code:
12352202
NACRES:
NA.25

Quality Level

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

sterile distilled water: soluble

shipped in

wet ice

storage temp.

2-8°C

General description

Do not disturb until the fibrinogen is completely solubilized.
Native fibrinogen from bovine plasma. A plasma glycoprotein synthesized and secreted by hepatic parenchymal cells. Fibrinogen, also known as Coagulation Factor I, is an acute-phase plasma protein found at a concentration of about 300 mg/100 ml. Conversion of soluble fibrinogen to the insoluble clot-forming fibrin is the terminal stage of blood clotting. Clinically, fibrinogen is elevated in pregnancy, after surgical trauma, and myocardial infarction, and is decreased in cases of liver cirrhosis and serum hepatitis.
Native fibrinogen from bovine plasma. An acute phase plasma glycoprotein synthesized and secreted by hepatic parenchymal cells. Contains ≥ 95% clottable proteins.

Warning

Toxicity: Harmful (C)

Physical form

Lyophilized from 20 mM sodium citrate-HCl, pH 7.4.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C) for long term storage or store at room temperature (20°C) for short term storage. Do not store solutions on ice; precipitation will occur. Stock solutions are stable for up to 4 h at 20°C or for up to 6 months at -20°C.
Solutions used to reconstitute fibrinogen should first be brought to 37°C. Once at 37°C, the solution can be added to the fibrinogen and this mixture should remain at 37°C until the fibrinogen is completely solubilized.

Analysis Note

homogeneous by SDS-PAGE.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

wgk_germany

WGK 3


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