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371708

Sigma-Aldrich

Gβγ Modulator II, Gallein

A cell-permeable xanthene compound that binds to Gβγ with high affinity (Kd ~400 nM derived from a surface plasma resonance binding study using Gβ1γ2) and blocks Gβγ-dependent cellular activities.

Synonym(s):

Gβγ Modulator II, Gallein, 4,5-Dihydroxyfluorescein, dihydrate, 2-(3,4,5-Trihydroxy-6-oxoxanthen-9-yl)-benzoic acid, dihydrate

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5 MG
$171.00

$171.00


Estimated to ship onJune 01, 2025


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5 MG
$171.00

About This Item

Empirical Formula (Hill Notation):
C20H12O7 · 2H2O
CAS Number:
Molecular Weight:
400.34
MDL number:
UNSPSC Code:
12171500
NACRES:
NA.77

$171.00


Estimated to ship onJune 01, 2025


Request a Bulk Order

Quality Level

assay

≥90% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

burgundy

solubility

DMSO: 10 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

O1C3(c4c(c(c(cc4)O)O)Oc5c3ccc(c5O)O)c2c(cccc2)C1=O

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This Item
324832218860654164
form

solid

form

solid

form

solid

form

solid

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 10 mg/mL

solubility

water: 1 mg/mL, DMSO: 25 mg/mL

solubility

DMSO: 50 mg/mL

solubility

DMSO: 10 mg/mL

General description

A cell-permeable xanthene compound that binds to Gβγ with high affinity (Kd ~400 nM derived from a surface plasma resonance binding study using Gβ1γ2) and blocks Gβγ-dependent cellular activities. Reported to exhibit in vivo prophylactic efficacy against carrageenan-induced neutrophil recruitment and tissue swelling in a murine paw edema model via either intraperitoneal or oral administration.

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Other Notes

Lehmann, D.M., et al. 2008. Mol. Pharmacol.73, 410.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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