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Sigma-Aldrich

Anti-Serum Amyloid P Component Rabbit pAb

liquid, Calbiochem®

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Synonym(s):
Anti-SAP

biological source

rabbit

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human

should not react with

mouse

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

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Anti-Collagen Type I Rabbit pAb

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

species reactivity

human

species reactivity

Drosophila, hamster, rat, human, monkey, mouse

species reactivity

-

species reactivity

mouse, human, rat

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−70°C

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

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General description

Rabbit polyclonal antibody supplied as undiluted serum. Recognizes serum amyloid P component.
Recognizes serum amyloid P component.
  • Antibody Target Gene Symbol: APCS
  • Target Synonym: MGC88159, PTX2, SAP, Serum amyloid p-component
  • Entrez Gene Name: amyloid P component, serum
  • Hu Entrez ID: 325
  • Mu Entrez ID: 20219
  • Rat Entrez ID: 29339
  • This Anti-Serum Amyloid P Component Rabbit pAb is validated for use in ELISA, Immunoelectrophoresis, IF, IHC, Ouchterlony, Radial Immunodiffusion for the detection of Serum Amyloid P Component.

    Immunogen

    Human
    purified human SAP component

    Application

    ELISA (see comments)

    Immunoelectrophoresis (see comments)

    Immunofluorescence (1:20-1:50)

    Immunohistochemistry (1:200)

    Ouchterlony (see comments)

    Radial Immunodiffusion (see comments)

    Warning

    Toxicity: Standard Handling (A)

    Physical form

    Undiluted serum.

    Reconstitution

    Following initial thaw, aliquot and freeze (-20°C).

    Other Notes

    Monospecific for serum amyloid P as determined by ouchterlony and immunoelectrophoresis. Immunofluorescence and immunoperoxidase staining of human tissues specifically identifies only those structures known to contain SAP. This antibody has also been reported to work for ELISA and radial immunodiffusion. Variables associated with assay conditions will dictate the optimal working dilution.
    Serban, D., and Rordorf-Adam, C. 1986. J. Immunol. Methods90, 159.
    Pepys, M.B., et al. 1979. Nature278, 259.

    Legal Information

    CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

    Storage Class

    10 - Combustible liquids

    wgk_germany

    WGK 1


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    Andrea Doni et al.
    Nature communications, 12(1), 3739-3739 (2021-06-20)
    Serum amyloid P component (SAP, also known as Pentraxin 2; APCS gene) is a component of the humoral arm of innate immunity involved in resistance to bacterial infection and regulation of tissue remodeling. Here we investigate the role of SAP
    Katrine Pilely et al.
    Frontiers in immunology, 8, 1040-1040 (2017-09-14)
    Inflammation is a part of the initial process leading to atherosclerosis and cholesterol crystals (CC), found in atherosclerotic plaques, which are known to induce complement activation. The pentraxins C-reactive protein (CRP), long pentraxin 3 (PTX3), and serum amyloid P component

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