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AB1526

Sigma-Aldrich

Anti-Nerve Growth Factor-β Antibody

serum, Chemicon®

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Synonym(s):
NGFbeta
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, rat, chicken, human

should not react with

bovine

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... NGF(4803)

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This Item
AB1528AB1526PSAB1306570
biological source

rabbit

biological source

sheep

biological source

rabbit

biological source

rabbit

antibody form

serum

antibody form

serum

antibody form

affinity purified immunoglobulin

antibody form

purified immunoglobulin

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

Gene Information

human ... NGF(4803)

Gene Information

human ... NGF(4803)

Gene Information

human ... NGF(4803)

Gene Information

human ... NGF(4803)

shipped in

wet ice

shipped in

dry ice

shipped in

dry ice

shipped in

wet ice

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Specificity

Nerve growth factor-beta (NGF). Less than 1% cross-reactivity against recombinant human NT3, NT4 and BDNF by ELISA.

Immunogen

Mouse nerve growth factor-beta purified from salivary glands.

Application

Immunohistochemistry at 1:500-1:5,000 (see suggested protocol).

Immunoblotting at 1:500-1:5,000.

ELISA at 1:500-1:5,000.

Inhibition of biological activity in vitro at 1:10-1:50.
BIOLOGICAL ACTIVITY: This antibody will completely inhibit the survival and neurite outgrowth actions of mouse NGF in chicken dorsal root ganglion neurons in vitro.

Use neat for in vivo animal studies.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
This Anti-Nerve Growth Factor-β Antibody is validated for use in ELISA, WB, IH, FUNC for the detection of Nerve Growth Factor-β.

Linkage

Replaces: 04-1119

Physical form

Whole rabbit antisera. Lyophilized. Reconstitute with 250 μL of sterile distilled water.

Storage and Stability

Maintain at -20°C to -70°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Tsia-Shu Lo et al.
The journal of obstetrics and gynaecology research, 43(1), 173-178 (2016-10-21)
By investigating the association of urodynamics and urogenital nerve growth factor (NGF) levels in vaginal mesh surgery, we may be able to associate the likelihood of postoperative lower urinary tract symptoms developing as a result of synthetic mesh implanted for
Sashwati Roy et al.
Nanomedicine : nanotechnology, biology, and medicine, 28, 102220-102220 (2020-05-19)
This work rests on our recent report on the successful use of tissue nanotransfection (TNT) delivery of Ascl1, Brn2, and Myt1l (TNTABM) to directly convert skin fibroblasts into electrophysiologically active induced neuronal cells (iN) in vivo. Here we report that
F Jardí et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 24(12), e580-e590 (2012-10-18)
Nerve growth factor (NGF)-mucosal mast cell (MMC) interaction has been implicated in the remodeling of enteric circuitries and associated functional changes. We investigated the involvement of NGF and its receptor TrkA in the altered colonic contractile activity observed in the
A Vega et al.
Developmental neurobiology, 76(8), 832-846 (2015-11-13)
Neurons are able to segregate transmitters to different axon endings. Segregation is a plastic neuronal feature; it can be modulated by synaptic environment. We have demonstrated that neurotrophin and other cellular factors regulate segregation in sympathetic neurons in culture. Herein
Daniel Aridgides et al.
PloS one, 8(2), e57450-e57450 (2013-02-26)
Cardiomyocytes express neurotrophin receptor TrkA that promotes survival following nerve growth factor (NGF) ligation. Whether TrkA also resides in cardiac fibroblasts (CFs) and underlies cardioprotection is unknown. To test whether CFs express TrkA that conveys paracrine signals to neighbor cardiomyocytes

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