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ECM644

Sigma-Aldrich

In Vitro Vascular Permeability Assay (24-well)

This In Vitro Vascular Permeability Assay kit employs a 24-well plate and provides an efficient system for evaluating the effects of chemicals & drug compounds on endothelial cell adsorption, transport & permeability.

Synonym(s):

Vascular permeability assay

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About This Item

UNSPSC Code:
12352207
eCl@ss:
32161000
NACRES:
NA.32

Quality Level

species reactivity (predicted by homology)

all

manufacturer/tradename

Chemicon®

technique(s)

cell based assay: suitable

detection method

fluorometric

shipped in

wet ice

Application

Research Category
Cell Structure
The Millipore® In Vitro Vascular Permeability Assay kit provides an efficient system for evaluating the effects of chemicals and drug compounds on endothelial cell adsorption, transport, and permeability. It is ideal for measuring compounds that may disrupt or protect an endothelial monolayer. Each In Vitro Vascular Permeability Assay Kit contains sufficient reagents for the evaluation of 24 samples. The In Vitro Vascular Permeability Assay Kit is intended for research use only, not for diagnostic or therapeutic applications.
This In Vitro Vascular Permeability Assay kit employs a 24-well plate and provides an efficient system for evaluating the effects of chemicals & drug compounds on endothelial cell adsorption, transport & permeability.

Components

24-Well Permeability Insert Assembly, Collagen-coated: One 24-well receiver tray containing 24 porous cell culture inserts pre-coated with type I rat-tail collagen.

Receiver Tray, 24-Well: Two 24-well plates.

FITC-Dextran Solution: One vial containing 250 µL.

Forceps: One set of forceps.

Cell Stain: One bottle containing 10 mL.

Black Plate, 96-Well Opaque: One 96-well plate.

Linkage

Replaces: ECM640

Storage and Stability

Store kit materials at 2-8°C; use within 4 months from date of receipt. Do not freeze.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Millipore is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10-13 - German Storage Class 10 to 13

wgk_germany

WGK 3


Certificates of Analysis (COA)

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Sabrina Rohringer et al.
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Bioscience, biotechnology, and biochemistry, 79(4), 581-586 (2014-12-17)
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Arteriosclerosis, thrombosis, and vascular biology, 38(11), 2665-2677 (2018-10-26)
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Luca Maroni et al.
The American journal of pathology, 187(2), 366-376 (2016-12-03)
Microbial products are thought to influence the progression of cholangiopathies, in particular primary sclerosing cholangitis (PSC). Inflammasomes are molecular platforms that respond to microbial products through the synthesis of proinflammatory cytokines. We investigated the role of inflammasome activation in cholangiocyte

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