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MAB1892

Sigma-Aldrich

Anti-Fibronectin Antibody, gelatin binding domain, clone IST-10

clone IST-10, Chemicon®, from mouse

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Synonym(s):
Anti-CIG, Anti-ED-B, Anti-FINC, Anti-FN, Anti-FNZ, Anti-GFND, Anti-GFND2, Anti-LETS, Anti-MSF, Anti-SMDCF
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

IST-10, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG1κ

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... FN1(2335)
mouse ... Fn1(14268)

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MAB1932F0916MAB1935
antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

ascites fluid

antibody form

purified antibody

species reactivity

human

species reactivity

canine, human

species reactivity

human

species reactivity

human

clone

IST-10, monoclonal

clone

875A51, monoclonal

clone

IST-4, monoclonal

clone

868A11, monoclonal

Gene Information

human ... FN1(2335)
mouse ... Fn1(14268)

Gene Information

human ... FN1(2335)

Gene Information

human ... FN1(2335)

Gene Information

human ... FN1(2335)

NCBI accession no.

NM_002026.2, NM_212474.1, NM_212476.1, NM_212482.1, NM_054034.2, NM_212478.1, NM_212475.1

NCBI accession no.

NM_002026.2, NM_054034.2, NM_212474.1, NM_212475.1, NM_212476.1, NM_212478.1, NM_212482.1

NCBI accession no.

-

NCBI accession no.

NM_002026.2, NM_054034.2, NM_212474.1, NM_212475.1, NM_212476.1, NM_212478.1, NM_212482.1

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Specificity

Recognizes an epitope contained within the gelatin binding domain of human fibronectin.

Immunogen

Epitope: gelatin binding domain

Application

Anti-Fibronectin Antibody, gelatin binding domain, clone IST-10 is an antibody against Fibronectin for use in WB, IH.
Immunohistochemistry

Immunoblotting: non-reducing conditions

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
ECM Proteins

Physical form

Format: Purified
Purified immunoglobulin in 0.02M phosphate buffer, 0.25M sodium chloride, 0.1% sodium azide, pH 7.6

Storage and Stability

Maintain between 2 and 8°C .

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Jane Sottile et al.
American journal of physiology. Cell physiology, 293(6), C1934-C1946 (2007-10-12)
Communication between cells and the extracellular matrix (ECM) is critical for regulation of cell growth, survival, migration, and differentiation. Remodeling of the ECM can occur under normal physiological conditions, as a result of tissue injury, and in certain pathological conditions.
Definition of the native and denatured type II collagen binding site for fibronectin using a recombinant collagen system.
An, B; Abbonante, V; Yigit, S; Balduini, A; Kaplan, DL; Brodsky, B
The Journal of Biological Chemistry null

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