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PC150

Sigma-Aldrich

Anti-β-Amyloid (1-42) Rabbit pAb

liquid, Calbiochem®

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biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

liquid

does not contain

preservative

species reactivity

human

packaging

antibody small pack of 25 μg

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... APP(351)

Related Categories

General description

Rabbit polyclonal antibody adsorbed against Aβ1-40 and Aβ1-43, followed by immunoaffinity purification. Recognizes specifically β-amyloid peptide (1-42).
Recognizes specifically β-amyloid peptide (1-42). Does not cross-react with β-amyloid peptide (1-40) or β-amyloid peptide (1-43).
  • Antibody Target Gene Symbol: APP
  • Target Synonym: AAA, AD1, Adap, AL024401, Amyloid precursor, Amyloidogenic glycoprotein, APP isoform 1, APPI, appican, CTFgamma, CVAP, E030013M08RIK, Nexin II, P3, PN2, PreA4, PROTEASE NEXIN2
  • Entrez Gene Name: amyloid beta (A4) precursor protein
  • Hu Entrez ID: 351 (Related Antibodies: 171610, PC729,PC152, PC151, PC149, NE1012,171609, 171608, 171607, 171606, 171605, 171604, 171603, 171598, 171537)
  • Mu Entrez ID: 11820
  • Rat Entrez ID: 54226
  • This Anti-β-Amyloid (1-42) Rabbit pAb is validated for use in Dot Blot, ELISA, Radioimmunoassay for the detection of β-Amyloid (1-42).

    Immunogen

    Human
    a synthetic peptide corresponding to amino acids from a C-terminal fragment of human β-amyloid peptide (1-42)

    Application

    Dot Blot (0.1-0.5 µg/ml)

    ELISA (0.1-0.5 µg/ml)

    Radioimmunoassay (0.5 µg/ml)

    Packaging

    Please refer to vial label for lot-specific concentration.

    Warning

    Toxicity: Standard Handling (A)

    Physical form

    In phosphate buffer, pH 7.4.

    Reconstitution

    Following initial thaw, aliquot and freeze (-20°C).

    Other Notes

    Savage, M.J., et al. 1998. J. Neurosci.15, 1743.
    Borchelt, D.R., et al. 1997. Neuron19, 939.
    Citron, M., et al. 1997. Nature Med.3, 67.
    Hardy, J. 1997. Trends in Neurosci.20, 154.
    Solomon, B., et al. 1997. Proc. Natl. Acad. Sci. USA94, 4109.
    Duff, K., et al. 1996. Nature383, 710.
    Iwatsubo, T., et al. 1994. Neuron13, 45.
    Suzuki, N., et al. 1994. Science264, 133.
    This antibody is specific for β-amyloid peptide [1-42] and shows no reactivity to β-amyloid peptide [1-40] or β-amyloid peptide [1-43]. This antibody is recommended for use in the quantitative determination of β-amyloid peptide [1-42]. The sensitivity level for sandwich ELISA is 15-25 pg. Antibody should be titrated for optimal results in individual systems.

    Legal Information

    CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

    Storage Class

    10 - Combustible liquids

    wgk_germany

    WGK 1

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable


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