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PYR0MATCELLS

Millipore

PyroMAT® cells

Cryopreserved MonoMac 6 cells for use in the Monocyte Activation Test (MAT) for Pyrogen testing, pkg of 2 vials

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eCl@ss:
32160606

Agency

EP Chapter 2.6.30

Quality Level

feature

ready-to-use

packaging

pkg of 2 vials

manufacturer/tradename

PyroMAT®

application(s)

pharmaceutical
pyrogen testing

compatibility

configured for PyroMAT® System

shipped in

dry ice

suitability

pyrogenic bacteria

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This Item
PYR0MATKITMATFLAGELLINMATHKSA
PyroMAT® cells Cryopreserved MonoMac 6 cells for use in the Monocyte Activation Test (MAT) for Pyrogen testing, pkg of 2 vials

Millipore

PYR0MATCELLS

PyroMAT® cells

PyroMAT® kit Reagents and Interleukin-6 ELISA kit for Monocyte Activation Test (MAT), for Pyrogen testing

Millipore

PYR0MATKIT

PyroMAT® kit

shipped in

dry ice

shipped in

ambient

shipped in

cooler

shipped in

ambient

Quality Level

400

Quality Level

400

Quality Level

400

Quality Level

400

agency

EP Chapter 2.6.30

agency

EP Chapter 2.6.30

agency

-

agency

-

feature

ready-to-use

feature

ready-to-use

feature

Non-endotoxin pyrogen control of flagellin for use in monocyte activation test

feature

Non-endotoxin pyrogen control of heat killed Staphyloccus aureus for use in monocyte activation test

manufacturer/tradename

PyroMAT®

manufacturer/tradename

PyroMAT®

manufacturer/tradename

PyroMAT®

manufacturer/tradename

PyroMAT®

General description

The PYROMAT® system is a robust, easy-to-perform and ready-to-use solution for pyrogen testing, using the Monocyte Activation Test (MAT). The PYROMAT® cells are cryopreserved human monocytic cells from the Mono-Mac-6 cell line. They have been validated to be used for MAT.
The PyroMAT® System is based on the Mono-Mac-6 (MM6) cell line and uses Interleukin-6 (IL-6) as a read out.
PyroMATcells contains the crypreserved MonoMac 6 cells, 2 x 1 mL

Application

PYROMAT® cells is used to determine the pyrogenic activity in a solution or suspension by inducing interleukin production in cell cultures with human monocytes. It is used to ensure the safety of parenteral pharmaceutical products and medical devices.

Features and Benefits

  • Cryopreserved ready-to-use monocytic cells
  • The only cell line validated and available for the Monocyte Activation Test
  • Expression of all the Toll-like Receptors responsible for pyrogen detection

Packaging

1 box of 2 vials, sufficient for 1 test

Components

2 vials of cryopreserved Mono-Mac-6 cells

Recommended products

To be used with PyroMAT kit (PYR0MATKIT), Reference standard endotoxin (144.161.0001), NEP controls (MATHKSA, MATFLAGELLIN)

Legal Information

PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Articles

What are primary cells? A comprehensive overview of animal and human primary cell lines and media and how they are used in biomedical cell culture applications. Primary cultures are less homogeneous relative to cell lines.

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