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05292

Sigma-Aldrich

Spermidine 0.1 M solution

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Synonym(s):
Spermidine solution, Additive Screening Solution 30/Kit-No 78374
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.32

Quality Level

density

1.00 g/mL at 20 °C

storage temp.

2-8°C

SMILES string

NCCCCNCCCN

InChI

1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2

InChI key

ATHGHQPFGPMSJY-UHFFFAOYSA-N

Gene Information

mouse ... Odc1(18263)
rat ... Ppm1a(24666)

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390590859163226
Spermidine 0.1 M solution

05292

Spermidine 0.1 M solution

Zinc chloride 0.1 M solution

39059

Zinc chloride 0.1 M solution

Sodium azide 0.1 M solution

08591

Sodium azide 0.1 M solution

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

-

Gene Information

mouse ... Odc1(18263)
rat ... Ppm1a(24666)

Gene Information

-

Gene Information

-

Gene Information

-

Biochem/physiol Actions

Spermidine is a naturally occurring polyamine. It is associated with various cellular functions. It is responsible for the condensation and aggregation of DNA in aqueous solution. Spermidine is known to extend lifespan via epigenetic modifications, induction of cell death and inhibition of necrosis.
Spermidine 0.1M solution is an additive screening solution of Additive Screening Kit. Additive Screen kit is designed to allow rapid and convenient evaluation of additives and their ability to influence the crystallization of the sample. The Additive Kit provides a tool for refining crystallization conditions.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Faceshields, Gloves, Goggles


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Induction of autophagy by spermidine promotes longevity.
Eisenberg T et al.
Nature Cell Biology, 11, 1305-1305 (2009)
53rd National Meeting of the Italian Society of Biochemistry and Molecular Biology (SIB) and National Meeting of Chemistry of Biological Systems ? Italian Chemical Society (SCI - Section CSB) (2008)
Satyanarayana U
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Transfer RNAs (tRNAs) are heavily decorated with post-transcriptional modifications during their biosynthesis. To fulfil their functions within cells, tRNAs undergo a tightly controlled biogenesis process leading to the formation of mature tRNAs. In addition, functions of tRNAs are often modulated
Lluís Millan-Ariño et al.
Current protocols in protein science, 102(1), e114-e114 (2020-10-01)
Histones are the major proteinaceous component of chromatin in eukaryotic cells and an important part of the epigenome, affecting most DNA-related events, including transcription, DNA replication, and chromosome segregation. The properties of histones are greatly influenced by their post-translational modifications

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