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14509

Sigma-Aldrich

Poly(ethylene glycol) bis(amine)

Mw 20,000

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Synonym(s):
O,O′-Bis(2-aminoethyl)polyethylene glycol, Diaminopolyethylene glycol, PEG-diamine, Polyoxyethylene bis(amine)
Linear Formula:
H2N(CH2CH2O)nCH2CH2NH2
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

mol wt

Mw 20,000

Quality Level

reaction suitability

reagent type: cross-linking reagent
reactivity: carboxyl reactive

Ω-end

amine

α-end

amine

polymer architecture

shape: linear
functionality: homobifunctional

InChI

1S/C6H16N2O2/c7-1-3-9-5-6-10-4-2-8/h1-8H2

Inchi Key

IWBOPFCKHIJFMS-UHFFFAOYSA-N

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This Item
1450214501P9906
vibrant-m

14509

Poly(ethylene glycol) bis(amine)

vibrant-m

14502

Poly(ethylene glycol) bis(amine)

vibrant-m

14501

Poly(ethylene glycol) bis(amine)

vibrant-m

P9906

Poly(ethylene glycol) bis(amine)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

Ω-end

amine

Ω-end

amine

Ω-end

amine

Ω-end

amine

α-end

amine

α-end

amine

α-end

amine

α-end

amine

mol wt

Mw 20,000

mol wt

Mw 3,000

mol wt

Mw 2,000

mol wt

average Mn 3400

reaction suitability

reagent type: cross-linking reagent
reactivity: carboxyl reactive

reaction suitability

reagent type: cross-linking reagent
reactivity: carboxyl reactive

reaction suitability

reagent type: cross-linking reagent
reactivity: carboxyl reactive

reaction suitability

reagent type: cross-linking reagent
reactivity: carboxyl reactive

application

With HCl, reduction agent; stereoselective allylation of carbonyl compounds; in situ generation of tinenolates for directed aldol reactions.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


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Huahua Jian et al.
The Journal of organic chemistry, 68(13), 5091-5103 (2003-06-21)
Four caltrop-shaped molecules that might be useful as surface-bound electric field-driven molecular motors have been synthesized. The caltrops are comprised of a pair of electron donor-acceptor arms and a tripod base. The molecular arms are based on a carbazole or
Yamamoto, Y.; Asao, N.
Chemical Reviews, 93, 2207-2207 (1993)
Phaedria M St Hilaire et al.
Journal of medicinal chemistry, 45(10), 1971-1982 (2002-05-03)
A one-bead-two-compound inhibitor library was synthesized by the split-mix method for the identification of inhibitors of a recombinant cysteine protease from Leishmania mexicana, CPB2.8DeltaCTE. The inhibitor library was composed of octapeptides with a centrally located reduced bond introduced by reductive
Stephen J Connon et al.
Bioorganic & medicinal chemistry letters, 12(14), 1873-1876 (2002-06-28)
The synthesis and olefin metathesis activity in protic solvents of 7, a phosphine-free ruthenium alkylidene bound to a hydrophilic solid support are reported. This heterogeneous catalyst promotes relatively efficient ring closing- and cross-metathesis reactions in both methanol and water. The
C S Lee et al.
Artificial organs, 21(9), 1002-1006 (1997-09-01)
Various modifications of alginate-poly-L-lysine microcapsules were made, such as the inclusion of polyethylenimine (PEI) or carboxyl methyl cellulose (CMC) in the core and the coating of bis(polyoxyethylene bis[amine]) (PEGA) onto the microcapsule membrane surface. A characterization of the modified microcapsules

Articles

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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