27690

2,4,6-Trimethylpyridine

puriss. p.a., 99% (GC)

• Synonym(s): 2,4,6-Collidine, sym-Collidine
• Empirical Formula (Hill Notation): C₈H₁₁N
• CAS Number: 108-75-8
• Molecular Weight: 121.18
• Beilstein/REAXYS Number: 107283
• EC Number: 203-613-3
• MDL number: MFCD00006338
• UNSPSC Code: 12352100
• PubChem Substance ID: 57648267
• NACRES: NA.21

Properties

• grade: puriss. p.a.
• Quality Level: 200
• assay: 99% (GC)
• form: liquid
• impurities: ≤0.1% water
• evapn. residue: ≤0.1%
• refractive index: n20/D 1.498 (lit.); n20/D 1.498
• bp: 171-172 °C (lit.)
• mp: −43 °C (lit.)
• density: 0.917 g/mL at 25 °C (lit.)
• cation traces: Al: ≤0.5 mg/kg; Ba: ≤0.1 mg/kg; Bi: ≤0.1 mg/kg; Ca: ≤0.5 mg/kg; Cd: ≤0.05 mg/kg; Co: ≤0.02 mg/kg; Cr: ≤0.02 mg/kg; Cu: ≤0.02 mg/kg; Fe: ≤0.1 mg/kg; K: ≤0.5 mg/kg; Li: ≤0.1 mg/kg; Mg: ≤0.1 mg/kg; Mn: ≤0.02 mg/kg; Mo: ≤0.1 mg/kg; Na: ≤0.5 mg/kg; Ni: ≤0.02 mg/kg; Pb: ≤0.1 mg/kg; Sr: ≤0.1 mg/kg; Zn: ≤0.1 mg/kg
• storage temp.: 2-8°C
• SMILES string: Cc1cc(C)nc(C)c1
• InChI: 1S/C8H11N/c1-6-4-7(2)9-8(3)5-6/h4-5H,1-3H3
• InChI key: BWZVCCNYKMEVEX-UHFFFAOYSA-N

Description

General description

2,4,6-Trimethylpyridine is a heterocyclic aromatic compound that is commonly used in dehydrohalogenation reactions. It is also used as a reaction solvent or chemical additive in organic reactions due to its basic properties.

Application

2,4,6-Trimethylpyridine can be used as a reagent:      

• In solid-phase peptide synthesis.     
• To synthesize trichloro(2,4,6-trimethylpyridine) Au(III) complex by reacting with HAuCl₄.

Tissue fixative for electron microscopy.

Safety Information

• pictograms: GHS02,GHS06
• signalword: Danger
• hcodes: H226,H302,H311,H315,H319,H335,H412
• pcodes: P210 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 131.0 °F - closed cup
• flash_point_c: 55 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter