MilliporeSigma
All Photos(1)

Documents

675415

Sigma-Aldrich

Acetonitrile

HPLC Plus, ≥99.9%, poly-coated bottles

Sign Into View Organizational & Contract Pricing

Synonym(s):
ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide
Linear Formula:
CH3CN
CAS Number:
Molecular Weight:
41.05
Beilstein/REAXYS Number:
741857
EC Number:
MDL number:
PubChem Substance ID:

grade

HPLC Plus

Quality Level

vapor density

1.41 (vs air)

vapor pressure

72.8 mmHg ( 20 °C)

assay

≥99.9%

form

liquid

autoignition temp.

525 °F
973 °F

expl. lim.

16 %

technique(s)

HPLC: suitable

impurities

≤0.01% water

evapn. residue

≤0.0002%

color

colorless

refractive index

n20/D 1.344 (lit.)

bp

81-82 °C (lit.)

mp

−45 °C (lit.)

solubility

water: soluble

density

0.786 g/mL at 25 °C (lit.)

absorption

≤1 mAU at 210 nm

UV absorption

λ: 195 nm Amax: ≤0.10
λ: 200 nm Amax: ≤0.02
λ: 228 nm Amax: ≤0.005

application(s)

food and beverages

format

neat

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
437557271004900667
vibrant-m

675415

Acetonitrile

vibrant-m

437557

Acetonitrile

vibrant-m

271004

Acetonitrile

vibrant-m

900667

Acetonitrile

grade

HPLC Plus

grade

ACS reagent

grade

anhydrous

grade

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

assay

≥99.9%

assay

≥99.5%

assay

99.8%

assay

≥99.92%

solubility

water: soluble

solubility

water: soluble

solubility

water: soluble (completely)

solubility

-

technique(s)

HPLC: suitable

technique(s)

solid phase extraction (SPE): suitable

technique(s)

solid phase extraction (SPE): suitable

technique(s)

mass spectrometry (MS): suitable

General description

Acetonitrile (MeCN), an aliphatic nitrile, is a colorless liquid with a pleasant odor. It is widely used as a solvent and intermediate in organic syntheses. It is transparent to UV-visible light making it highly applicable in spectrophotometric and fluorimetric techniques. As MeCN has low viscosity, high elution strength and is highly miscible in water, it is utilized as a mobile phase component in many chromatographic techniques. Its infrared spectrum has been recorded. Synthesis of alkyl hydroperoxides in MeCN by alkane oxidation with hydrogen peroxide in the presence of iron complexes has been studied. The hydrogenation of MeCN to form ethylamine using Co–B amorphous alloy catalyst has been investigated.

pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2.0 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 4

1 of 4

Acetonitrile electronic grade, 99.999% trace metals basis

Sigma-Aldrich

733466

Acetonitrile

Acetonitrile ReagentPlus®, 99%

Sigma-Aldrich

110086

Acetonitrile

Acetonitrile for preparative chromatography Prepsolv™

Supelco

1.13358

Acetonitrile

Acetonitrile OmniSolv® LC-MS

Supelco

AX0156

Acetonitrile

Liquid phase hydrogenation of acetonitrile to ethylamine over the Co-B amorphous alloy catalyst.
Li H, et al.
J. Catal., 214(1), 15-25 (2003)
Hydrogen peroxide oxygenation of alkanes including methane and ethane catalyzed by iron complexes in acetonitrile.
Shul'pin GB, et al.
Advanced Synthesis & Catalysis, 346(2-3), 317-332 (2004)
Infrared spectra of acetonitrile and acetonitrile-d3.
Pace EL and Noe LJ.
J. Chem. Phys. , 49, 5317-5325 (1968)
Eagleson M.
Concise Encyclopedia Chemistry, 6-6 (1994)
Purification of acetonitrile.
Walter M and Ramaley L.
Analytical Chemistry, 45(1), 165-166 (1973)

Related Content

The application note describes the separation of Ibuprofen and its related impurities using an Ascentis® Express 90Å C18 column with excellent peak shape and limits of quantification of 1 ppm or less.

Chromatograms

application for HPLC

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service