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69478

Supelco

N-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane

for GC derivatization, LiChropur

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Empirical Formula (Hill Notation):
C6H12F3NOSi
CAS Number:
Molecular Weight:
199.25
Beilstein/REAXYS Number:
1941550
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

grade

for GC derivatization

assay

≥97.0%

form

liquid

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.378

SMILES string

CN(C(=O)C(F)(F)F)[Si](C)(C)C

InChI

1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3

InChI key

MSPCIZMDDUQPGJ-UHFFFAOYSA-N

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This Item
69479M78918.41102
vibrant-m

M7891

N-Methyl-N-(trimethylsilyl)trifluoroacetamide

Essential+ Grade
reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

reaction suitability

-

reaction suitability

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

refractive index

n20/D 1.378

refractive index

n20/D 1.38 (lit.), n20/D 1.380

refractive index

n20/D 1.38 (lit.)

refractive index

-

form

liquid

form

liquid

form

liquid

form

liquid

grade

for GC derivatization

grade

for GC derivatization

grade

-

grade

-

General description

Silylation can be performed by adding N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MTFA) during analysis of fluorometabolites via gas chromatography-mass spectrometry (GC-MS).

Application

Addition of Trimethylchlorosilane aids in the derivatization of amides, secondary amines and hindered hydroxy groups. Most volatile of the TMS derivatives often elutes at the solvent front of the GC.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

related product

pictograms

FlameExclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

78.8 °F - closed cup

flash_point_c

26 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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