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81172

Sigma-Aldrich

Poly(ethylene glycol)

tested according to Ph. Eur., 400

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Synonym(s):
Macrogol 400, PEG
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Agency

tested according to Ph. Eur.

Quality Level

form

liquid

mol wt

380-420

application(s)

pharmaceutical (small molecule)

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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This Item
20239895904P3515
Poly(ethylene glycol) tested according to Ph. Eur., 400

Sigma-Aldrich

81172

Poly(ethylene glycol)

-
Poly(ethylene glycol) average Mn 400

Sigma-Aldrich

202398

Poly(ethylene glycol)

-
Poly(ethylene glycol) BioUltra, 4,000

Sigma-Aldrich

95904

Poly(ethylene glycol)

Premium Grade
Poly(ethylene glycol) average Mn 950-1,050

Sigma-Aldrich

P3515

Poly(ethylene glycol)

-
mol wt

380-420

mol wt

Mn 380-420, average Mn 400

mol wt

Mr 3500-4500

mol wt

average Mn 950-1,050

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

agency

tested according to Ph. Eur.

agency

-

agency

-

agency

-

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-

application(s)

-

General description

Polyethylene glycol (PEG) is a polyether compound with repeated ethylene glycol units[-(CH2CH2O)n].

Application

Poly(ethylene glycol) has been used as a liquid medium to prepare shear thickening fluid (STF) by directly mixing it with fumica silica.

Biochem/physiol Actions

Polyethylene glycol (PEG) is a synthetic polymer and is used as an additive in food, cosmetics, and pharmaceuticals. It is also involved in biomedical applications like biosensing, imaging, and tissue engineering. PEG is used as a gold standard in bioconjugation and nanomedicine thereby increasing blood circulation time and improving drug efficacy. PEG-conjugated drugs are approved by the U.S. Food and Drug Administration (FDA). They are considered safe for use in humans. PEG reduces the liver uptake and repels protein adsorption, which makes it useful in nanocoating.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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The ballistic performance of aramid based fabrics impregnated with multi-phase shear thickening fluids
Gurgen S and Kucshan MC
Polymer Testing, 64, 296-306 (2017)
The rheology of shear thickening fluids with various ceramic particle additives
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Poly(ethylene glycol) (PEG) is widely used as a gold standard in bioconjugation and nanomedicine to prolong blood circulation time and improve drug efficacy. The conjugation of PEG to proteins, peptides, oligonucleotides (DNA, small interfering RNA (siRNA), microRNA (miRNA)) and nanoparticles
Janina-Miriam Noy et al.
Biomacromolecules, 21(6), 2320-2333 (2020-04-29)
Phosphorylcholine is known to repel the absorption of proteins onto surfaces, which can prevent the formation of a protein corona on the surface of nanoparticles. This can influence the fate of nanoparticles used for drug delivery. This material could therefore

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